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General | Insiders | Insider Transactions | Monthly Overview | Weekly Overview

Overview of all insider trading transactions in ALNYLAM PHARMACEUTICALS, INC.. Get notifications about new insider transactions in ALNYLAM PHARMACEUTICALS, INC. for free.

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Date	Ticker	Company	Owner	Relationship	Transaction	Code	Cost ($)	Shares	Transaction Value ($)	Total Shares	% Holdings
May 17 2017	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, R&D	Sell	S	65.00	32,750	2,128,750	10,297	43 K to 10.3 K (-76.08 %)
May 17 2017	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, R&D	Buy	M	31.39	32,750	1,028,023	43,047	10.3 K to 43 K (+318.05 %)
Feb 03 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	M	31.29	25,000	782,250	0
Feb 03 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	S	40.16	4,829	193,933	140,795	145.6 K to 140.8 K (-3.32 %)
Feb 03 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	S	39.72	20,171	801,192	145,624	165.8 K to 145.6 K (-12.17 %)
Feb 03 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	M	31.29	25,000	782,250	165,795	140.8 K to 165.8 K (+17.76 %)
Jan 27 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	M	31.39	15,000	470,850	0
Jan 27 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	S	37.95	15,000	569,250	140,795	155.8 K to 140.8 K (-9.63 %)
Jan 27 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	M	31.39	15,000	470,850	155,795	140.8 K to 155.8 K (+10.65 %)
Jan 20 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	M	15.91	15,000	238,650	0
Jan 20 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	S	38.20	6,200	236,840	140,795	147 K to 140.8 K (-4.22 %)
Jan 20 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	S	37.57	8,800	330,616	146,995	155.8 K to 147 K (-5.65 %)
Jan 20 2017	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	M	15.91	15,000	238,650	155,795	140.8 K to 155.8 K (+10.65 %)
Jan 06 2017	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	18.66	1,340	25,004	144,641
Jan 06 2017	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	18.66	1,340	25,004	149,710	148.4 K to 149.7 K (+0.90 %)
Jan 04 2017	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D	Option Exercise	M	21.35	4,356	93,001	55,994
Jan 04 2017	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D	Option Exercise	M	18.66	4,019	74,995	45,981
Jan 04 2017	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D	Option Exercise	M	16.43	1,172	19,256	38,913
Jan 04 2017	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D	Payment of Exercise	F	37.44	5,000	187,200	10,297	15.3 K to 10.3 K (-32.69 %)
Jan 04 2017	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D	Buy	M	21.35	4,356	93,001	15,297	10.9 K to 15.3 K (+39.81 %)
Jan 04 2017	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D	Buy	M	18.66	4,019	74,995	10,941	6.9 K to 10.9 K (+58.06 %)
Jan 04 2017	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D	Buy	M	16.43	1,172	19,256	6,922	5.8 K to 6.9 K (+20.38 %)
Jan 03 2017	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	A	0.00	8,502	0	8,502
Dec 22 2016	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	A	42.22	5,550	234,321	5,550
Dec 22 2016	ALNY	ALNYLAM PHARMACEUT ...	Gros David-Alexandre C	SVP, Chief Business ...	Option Exercise	A	42.22	25,000	1,055,500	25,000
Dec 22 2016	ALNY	ALNYLAM PHARMACEUT ...	KEATING LAURIE	SVP, GC & Secretary	Option Exercise	A	42.22	25,000	1,055,500	25,000
Dec 22 2016	ALNY	ALNYLAM PHARMACEUT ...	Greenstreet Yvonne	EVP, Chief Commerci ...	Option Exercise	A	42.22	25,000	1,055,500	25,000
Dec 22 2016	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Option Exercise	A	42.22	25,000	1,055,500	25,000
Dec 22 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President	Option Exercise	A	42.22	25,000	1,055,500	25,000
Dec 22 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	A	42.22	25,000	1,055,500	25,000
Dec 14 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	22.75	30,151	685,935	0
Dec 14 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Payment of Exercise	F	42.61	22,710	967,673	148,370	171.1 K to 148.4 K (-13.27 %)
Dec 14 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	22.75	30,151	685,935	171,080	140.9 K to 171.1 K (+21.39 %)
Dec 05 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President	Option Exercise	M	22.75	55,605	1,265,014	0
Dec 05 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President	Sell	S	44.07	500	22,036	88,584	89.1 K to 88.6 K (-0.56 %)
Dec 05 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President	Sell	S	43.28	16,976	734,747	89,084	106.1 K to 89.1 K (-16.01 %)
Dec 05 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President	Sell	S	42.61	14,349	611,345	106,060	120.4 K to 106.1 K (-11.92 %)
Dec 05 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President	Buy	M	22.75	55,605	1,265,014	120,409	64.8 K to 120.4 K (+85.80 %)
Dec 02 2016	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Option Exercise	M	22.75	29,165	663,504	0
Dec 02 2016	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Sell	S	46.14	1,500	69,208	5,750	7.3 K to 5.8 K (-20.69 %)
Dec 02 2016	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Sell	S	45.55	13,297	605,662	7,250	20.5 K to 7.3 K (-64.72 %)
Dec 02 2016	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Sell	S	44.34	14,368	637,127	20,547	34.9 K to 20.5 K (-41.15 %)
Dec 02 2016	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Buy	M	22.75	29,165	663,504	34,915	5.8 K to 34.9 K (+507.22 %)
Oct 14 2016	ALNY	ALNYLAM PHARMACEUT ...	PYOTT DAVID E I	Director	Buy	P	37.00	27,900	1,032,328	27,900	0 to 27.9 K
Oct 14 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	18.66	4,019	74,995	145,981
Oct 14 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	7.10	3,521	24,999	135,915
Oct 14 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	18.66	4,019	74,995	140,929	136.9 K to 140.9 K (+2.94 %)
Oct 14 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	7.10	3,521	24,999	136,910	133.4 K to 136.9 K (+2.64 %)
Sep 21 2016	ALNY	ALNYLAM PHARMACEUT ...	Greenstreet Yvonne	EVP, Chief Operatin ...	Option Exercise	A	77.10	125,000	9,637,500	125,000
Jul 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	22.75	15,075	342,956	30,151
Jul 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	22.75	15,076	342,979	45,226
Jul 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	66.00	2,418	159,586	133,389	135.8 K to 133.4 K (-1.78 %)
Jul 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	65.56	12,057	790,430	135,807	147.9 K to 135.8 K (-8.15 %)
Jul 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	64.29	600	38,575	147,864	148.5 K to 147.9 K (-0.40 %)
Jul 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	22.75	15,075	342,956	148,464	133.4 K to 148.5 K (+11.30 %)
Jul 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	64.56	1,505	97,159	133,389	134.9 K to 133.4 K (-1.12 %)
Jul 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	63.73	13,571	864,839	134,894	148.5 K to 134.9 K (-9.14 %)
Jul 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	22.75	15,076	342,979	148,465	133.4 K to 148.5 K (+11.30 %)
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	SCHULMAN AMY W	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	PYOTT DAVID E I	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	PAUL STEVEN M	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	Fanucci Marsha	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	CLARKE JOHN K	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	BONNEY MICHAEL W	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Jun 07 2016	ALNY	ALNYLAM PHARMACEUT ...	Ausiello Dennis A	Director	Option Exercise	A	70.20	11,250	789,750	11,250
Mar 28 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	M	9.14	8,940	81,712	89,060
Mar 28 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	M	7.10	7,600	53,960	92,400
Mar 28 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	M	7.10	7,600	53,960	64,804	57.2 K to 64.8 K (+13.29 %)
Mar 28 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	M	9.14	8,940	81,712	57,204	48.3 K to 57.2 K (+18.52 %)
Mar 10 2016	ALNY	ALNYLAM PHARMACEUT ...	BONNEY MICHAEL W	Director	Buy	P	58.36	2,000	116,720	4,000	2 K to 4 K (+100.00 %)
Feb 25 2016	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Option Exercise	A	94.14	10,000	941,400	10,000
Feb 24 2016	ALNY	ALNYLAM PHARMACEUT ...	Gros David-Alexandre C	SVP, Chief Business ...	Buy	P	62.75	900	56,475	1,000	100 to 1,000 (+900.00 %)
Feb 24 2016	ALNY	ALNYLAM PHARMACEUT ...	Gros David-Alexandre C	SVP, Chief Business ...	Buy	P	62.74	100	6,274	100	0 to 100
Feb 24 2016	ALNY	ALNYLAM PHARMACEUT ...	ALNYLAM PHARMACEUTICALS, INC.	10% Owner	Sell	S	7.18	1,000,000	7,180,000	4,896,716	5.9 M to 4.9 M (-16.96 %)
Feb 03 2016	ALNY	ALNYLAM PHARMACEUT ...	KEATING LAURIE	SVP, GC & Secretary	Option Exercise	A	96.45	1,987	191,646	1,987
Feb 03 2016	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	A	96.45	2,750	265,238	2,750
Feb 03 2016	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Option Exercise	A	96.45	11,709	1,129,333	11,709
Feb 03 2016	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	A	96.45	15,875	1,531,144	15,875
Feb 03 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	A	96.45	25,000	2,411,250	25,000
Feb 03 2016	ALNY	ALNYLAM PHARMACEUT ...	Sanofi	10% Owner	Buy	P	69.75	205,030	14,300,843	10,256,633	10.1 M to 10.3 M (+2.04 %)
Apr 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	22.75	15,075	342,956	60,302
Apr 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	22.75	15,076	342,979	75,377
Apr 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	68.24	2,405	164,128	133,389	135.8 K to 133.4 K (-1.77 %)
Apr 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	67.38	12,670	853,645	135,794	148.5 K to 135.8 K (-8.53 %)
Apr 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	22.75	15,075	342,956	148,464	133.4 K to 148.5 K (+11.30 %)
Apr 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	68.71	300	20,612	133,389	133.7 K to 133.4 K (-0.22 %)
Apr 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	68.00	5,405	367,555	133,689	139.1 K to 133.7 K (-3.89 %)
Apr 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	67.02	9,371	628,032	139,094	148.5 K to 139.1 K (-6.31 %)
Apr 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	22.75	15,076	342,979	148,465	133.4 K to 148.5 K (+11.30 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	22.75	15,076	342,979	90,453
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	22.75	15,076	342,979	105,529
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	74.61	325	24,249	133,389	133.7 K to 133.4 K (-0.24 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	73.77	1,865	137,577	133,714	135.6 K to 133.7 K (-1.38 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	72.51	400	29,005	135,579	136 K to 135.6 K (-0.29 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	71.79	1,136	81,548	135,979	137.1 K to 136 K (-0.83 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	70.43	930	65,498	137,115	138 K to 137.1 K (-0.67 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	69.40	2,114	146,704	138,045	140.2 K to 138 K (-1.51 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	68.35	4,406	301,155	140,159	144.6 K to 140.2 K (-3.05 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	67.39	2,700	181,961	144,565	147.3 K to 144.6 K (-1.83 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	66.28	1,200	79,537	147,265	148.5 K to 147.3 K (-0.81 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	22.75	15,076	342,979	148,465	133.4 K to 148.5 K (+11.30 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	78.04	200	15,608	133,389	133.6 K to 133.4 K (-0.15 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	76.95	200	15,390	133,589	133.8 K to 133.6 K (-0.15 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	75.97	2,245	170,550	133,789	136 K to 133.8 K (-1.65 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	75.01	3,400	255,050	136,034	139.4 K to 136 K (-2.44 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	74.14	5,112	378,993	139,434	144.5 K to 139.4 K (-3.54 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	73.03	1,281	93,546	144,546	145.8 K to 144.5 K (-0.88 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	71.81	800	57,447	145,827	146.6 K to 145.8 K (-0.55 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	70.95	1,838	130,401	146,627	148.5 K to 146.6 K (-1.24 %)
Jan 21 2016	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	22.75	15,076	342,979	148,465	133.4 K to 148.5 K (+11.30 %)
Dec 22 2015	ALNY	ALNYLAM PHARMACEUT ...	KEATING LAURIE	SVP, GC & Secretary	Option Exercise	A	88.95	14,000	1,245,300	14,000
Dec 22 2015	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	A	88.95	7,200	640,440	7,200
Dec 22 2015	ALNY	ALNYLAM PHARMACEUT ...	Gros David-Alexandre C	SVP, Chief Business ...	Option Exercise	A	88.95	15,012	1,335,317	15,012
Dec 22 2015	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Option Exercise	A	88.95	30,000	2,668,500	30,000
Dec 22 2015	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	A	88.95	40,000	3,558,000	40,000
Dec 22 2015	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Gift	G	0.00	2,100	0	48,264	50.4 K to 48.3 K (-4.17 %)
Dec 22 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	A	88.95	65,000	5,781,750	65,000
Dec 22 2015	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Gift	G	0.00	4,000	0	306,996	311 K to 307 K (-1.29 %)
Dec 22 2015	ALNY	ALNYLAM PHARMACEUT ...	PYOTT DAVID E I	Director	Option Exercise	A	88.95	25,000	2,223,750	25,000
Dec 09 2015	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	A	97.72	10,000	977,200	10,000
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	M	14.74	10,000	147,400	0
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	M	14.05	20,000	281,000	0
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	S	109.00	30,000	3,270,000	140,795	170.8 K to 140.8 K (-17.56 %)
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	M	14.05	20,000	281,000	170,795	150.8 K to 170.8 K (+13.26 %)
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	M	14.74	10,000	147,400	150,795	140.8 K to 150.8 K (+7.10 %)
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	13.12	58,689	770,000	0
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	106.60	700	74,622	133,389	134.1 K to 133.4 K (-0.52 %)
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	106.02	16,984	1,800,596	134,089	151.1 K to 134.1 K (-11.24 %)
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	105.16	20,238	2,128,192	151,073	171.3 K to 151.1 K (-11.81 %)
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	104.00	10,784	1,121,541	171,311	182.1 K to 171.3 K (-5.92 %)
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	103.15	9,983	1,029,764	182,095	192.1 K to 182.1 K (-5.20 %)
Dec 04 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	13.12	58,689	770,000	192,078	133.4 K to 192.1 K (+44.00 %)
Nov 30 2015	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Option Exercise	M	22.75	835	18,996	29,165
Nov 30 2015	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Option Exercise	M	16.43	4,915	80,753	40,085
Nov 30 2015	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Buy	M	16.43	4,915	80,753	5,750	835 to 5.8 K (+588.62 %)
Nov 30 2015	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, R&D, CMO	Buy	M	22.75	835	18,996	835	0 to 835
Nov 20 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	7.10	10,564	75,004	139,436
Nov 20 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	13.12	58,690	770,013	58,689
Nov 20 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	103.97	8,070	839,023	133,389	141.5 K to 133.4 K (-5.70 %)
Nov 20 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	103.13	23,483	2,421,832	141,459	164.9 K to 141.5 K (-14.24 %)
Nov 20 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	102.34	27,137	2,777,078	164,942	192.1 K to 164.9 K (-14.13 %)
Nov 20 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	7.10	10,564	75,004	192,079	181.5 K to 192.1 K (+5.82 %)
Nov 20 2015	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	13.12	58,690	770,013	181,515	122.8 K to 181.5 K (+47.78 %)
Nov 13 2015	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	M	9.30	25,000	232,500	0
Nov 13 2015	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	M	15.82	25,000	395,500	0
Nov 13 2015	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	M	11.33	12,500	141,625	0
Nov 13 2015	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	M	11.33	12,500	141,625	12,500

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