BAKER BROS ADVISORS LLC Insider Trading

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General | Insider Transactions | Monthly Overview

Get the latest insider transactions of BAKER BROS ADVISORS LLC. BAKER BROS ADVISORS LLC is a 10% Owner in BIOCRYST PHARMACEUTICALS INC ($BCRX) and a Director in INCYTE CORP ($INCY) and a Director in ALEXION PHARMACEUTICALS INC ($ALXN) and a 10% Owner in IDERA PHARMACEUTICALS, INC. ($IDRA) and a Director in IDERA PHARMACEUTICALS, INC. ($IDRA) and a in XOMA Corp ($XOMA) and a Director in ACADIA PHARMACEUTICALS INC ($ACAD) and a Director in SEATTLE GENETICS INC /WA ($SGEN) and a Director in GENOMIC HEALTH INC ($GHDX) and a 10% Owner in BELLICUM PHARMACEUTICALS, INC ($BLCM) and a 10% Owner in AQUINOX PHARMACEUTICALS, INC ($AQXP) and a Director in AQUINOX PHARMACEUTICALS, INC ($AQXP) and a Director in Zymeworks Inc. ($ZYME) and a Director in Kodiak Sciences Inc. ($KOD) and a 10% Owner in Invitae Corp ($NVTA) and a Director in IGM Biosciences, Inc. ($IGMS) and a 10% Owner in Atreca, Inc. ($BCEL) and a in Mirati Therapeutics, Inc. ($MYG) and a 10% Owner in Mirati Therapeutics, Inc. ($MYG) and a Director in Talis Biomedical Corp ($TLIS) and a Director in Aeglea BioTherapeutics, Inc. ($AGLE) and a in RHYTHM PHARMACEUTICALS, INC. ($RYTM) and a in Intellia Therapeutics, Inc. ($NTLA) and a Director in BeiGene, Ltd. ($BGNE) and a Director in Prelude Therapeutics Inc ($PRLD) and a Director in Kiniksa Pharmaceuticals, Ltd. ($KNSA) and a in HOOKIPA Pharma Inc. ($HOOK).

Over the past year BAKER BROS ADVISORS LLC has been an insider in 14 companies. The total value of shares held by BAKER BROS ADVISORS LLC in these companies amounts to $851,619,434.

BAKER BROS ADVISORS LLC Director
ACADIA PHARMACEUTICALS INC
Director
Aeglea BioTherapeutics, Inc.
Director
ALEXION PHARMACEUTICALS, INC.
10% Owner
Atreca, Inc.
Director
BeiGene, Ltd.
10% Owner
BELLICUM PHARMACEUTICALS, INC
10% Owner
BIOCRYST PHARMACEUTICALS INC
Director
GENOMIC HEALTH INC
HOOKIPA Pharma Inc.
10% Owner, Director
IDERA PHARMACEUTICALS, INC.
Director
IGM Biosciences, Inc.
Director
INCYTE CORP
Intellia Therapeutics, Inc.
10% Owner
Invitae Corp
Director
Kiniksa Pharmaceuticals, Ltd.
Director
Kodiak Sciences Inc.
Mirati Therapeutics, Inc.
Director, 10% Owner
Neoleukin Therapeutics, Inc.
Director
Prelude Therapeutics Inc
RHYTHM PHARMACEUTICALS, INC.
Director
Seagen Inc.
Director
Talis Biomedical Corp
XOMA Corp
Director
Zymeworks Inc.
$ 851619434 The total value of shares held by BAKER BROS ADVISORS LLC
Insider Rank

BAKER BROS ADVISORS LLC ranks 88 out of 350,000 insiders. Go to Insider Ranking to see more.

Address: 667 MADISON AVENUE 21ST FLOOR NEW YORK US 10065 NY

Companies in which BAKER BROS ADVISORS LLC is an Insider

ACADIA PHARMACEUTICALS INC

Trading Symbol: ACAD
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 3,476,727 shares
Current Value: $132,776,204
Latest Transaction: Jun 25 2020
$ACAD Market Capitalization: $4.67B
$ACAD Previous Close: $38.19

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 65x
Sell: 4x
Shares Bought: 20,024,057
Shares Sold: 969,131
Share Difference: +19,054,926
Value Difference: -$401,044,308

Aeglea BioTherapeutics, Inc.

Trading Symbol: AGLE
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 0 shares
Current Value: $0
Latest Transaction: Feb 25 2021
$AGLE Market Capitalization: $56.54M
$AGLE Previous Close: $4.19

Last 4 weeks trend: HOLD
Last 3 months trend: HOLD View transactions

ALEXION PHARMACEUTICALS, INC.

Trading Symbol: ALXN
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 997,764 shares
Current Value: $127,434,418
Latest Transaction: May 18 2020
$ALXN Market Capitalization: $28.30B
$ALXN Previous Close: $127.72

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 72x
Sell: 18x
Shares Bought: 1,866,677
Shares Sold: 300,000
Share Difference: +1,566,677
Value Difference: -$159,256,868

Atreca, Inc.

Trading Symbol: BCEL
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: 10% Owner
Holdings: 309,730 shares
Latest Transaction: Jul 20 2020

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 2x
Sell: 0x
Shares Bought: 3,532,760
Shares Sold: 0
Share Difference: +3,532,760
Value Difference: $0

BeiGene, Ltd.

Trading Symbol: BGNE
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 10,418 shares
Current Value: $374,215
Latest Transaction: Dec 04 2020
$BGNE Market Capitalization: $1.14B
$BGNE Previous Close: $35.92

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 18x
Sell: 7x
Shares Bought: 24,479,643
Shares Sold: 2,352,517
Share Difference: +22,127,126
Value Difference: -$771,007,272

BELLICUM PHARMACEUTICALS, INC

Trading Symbol: BLCM
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: 10% Owner
Holdings: 412,246 shares
Current Value: $5,181,932
Latest Transaction: Jan 19 2018
$BLCM Market Capitalization: $335.83M
$BLCM Previous Close: $12.57

Last 4 weeks trend: STRONG SELL
Last 3 months trend: STRONG SELL View transactions

Last 3 Months Overview:
Buy: 2x
Sell: 9x
Shares Bought: 166,666
Shares Sold: 880,735
Share Difference: -714,069
Value Difference: +$5,219,903

BIOCRYST PHARMACEUTICALS INC

Trading Symbol: BCRX
Industry: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
Position of BAKER BROS ADVISORS LLC: 10% Owner
Holdings: 1,656,688 shares
Current Value: $9,393,421
Latest Transaction: Aug 16 2016
$BCRX Market Capitalization: $427.06M
$BCRX Previous Close: $5.67

Last 4 weeks trend: STRONG SELL
Last 3 months trend: STRONG SELL View transactions

Last 3 Months Overview:
Buy: 0x
Sell: 8x
Shares Bought: 0
Shares Sold: 4,046,590
Share Difference: -4,046,590
Value Difference: +$20,251,102

GENOMIC HEALTH INC

Trading Symbol: GHDX
Industry: SERVICES-MEDICAL LABORATORIES [8071]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 165,980 shares
Current Value: $4,562,790
Latest Transaction: Oct 03 2019
$GHDX Market Capitalization: $928.37M
$GHDX Previous Close: $27.49

Last 4 weeks trend: STRONG SELL
Last 3 months trend: STRONG SELL View transactions

Last 3 Months Overview:
Buy: 63x
Sell: 615x
Shares Bought: 161,439
Shares Sold: 4,679,162
Share Difference: -4,517,723
Value Difference: +$329,841,472

HOOKIPA Pharma Inc.

Trading Symbol: HOOK
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC:
Holdings: 72,128 shares
Latest Transaction: Apr 23 2019

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 2x
Sell: 0x
Shares Bought: 892,857
Shares Sold: 0
Share Difference: +892,857
Value Difference: -$12,499,998

IDERA PHARMACEUTICALS, INC.

Trading Symbol: IDRA
Industry: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
Position of BAKER BROS ADVISORS LLC: 10% Owner, Director
Holdings: 350,721 shares
Current Value: $547,125
Latest Transaction: Jul 03 2019
$IDRA Market Capitalization: $230.34M
$IDRA Previous Close: $1.56

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 30x
Sell: 2x
Shares Bought: 28,562,769
Shares Sold: 238,234
Share Difference: +28,324,535
Value Difference: -$21,972,994

IGM Biosciences, Inc.

Trading Symbol: IGMS
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 267,065 shares
Latest Transaction: Feb 23 2021

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 12x
Sell: 0x
Shares Bought: 3,167,758
Shares Sold: 0
Share Difference: +3,167,758
Value Difference: -$50,945,854

INCYTE CORP

Trading Symbol: INCY
Industry: SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 2,850,042 shares
Current Value: $336,817,964
Latest Transaction: Oct 02 2020
$INCY Market Capitalization: $23.12B
$INCY Previous Close: $118.18

Last 4 weeks trend: STRONG SELL
Last 3 months trend: STRONG SELL View transactions

Last 3 Months Overview:
Buy: 44x
Sell: 2x
Shares Bought: 693,867
Shares Sold: 2,295,944
Share Difference: -1,602,077
Value Difference: -$14,729,858

Intellia Therapeutics, Inc.

Trading Symbol: NTLA
Industry: IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
Position of BAKER BROS ADVISORS LLC:
Holdings: 976,214 shares
Current Value: $12,983,646
Latest Transaction: May 11 2016
$NTLA Market Capitalization: $471.17M
$NTLA Previous Close: $13.30

Last 4 weeks trend: HOLD
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 4x
Sell: 0x
Shares Bought: 1,062,120
Shares Sold: 0
Share Difference: +1,062,120
Value Difference: -$3,600,000

Invitae Corp

Trading Symbol: NVTA
Industry: SERVICES-MEDICAL LABORATORIES [8071]
Position of BAKER BROS ADVISORS LLC: 10% Owner
Holdings: 845,858 shares
Current Value: $7,443,550
Latest Transaction: Mar 29 2018
$NVTA Market Capitalization: $281.95M
$NVTA Previous Close: $8.80

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 4x
Sell: 0x
Shares Bought: 1,844,444
Shares Sold: 0
Share Difference: +1,844,444
Value Difference: -$9,399,998

Kiniksa Pharmaceuticals, Ltd.

Trading Symbol: KNSA
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 98,980 shares
Latest Transaction: Jul 28 2020

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 4x
Sell: 1x
Shares Bought: 3,029,680
Shares Sold: 200,423
Share Difference: +2,829,257
Value Difference: -$54,000,000

Kodiak Sciences Inc.

Trading Symbol: KOD
Industry: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 1,024,982 shares
Latest Transaction: Sep 25 2020

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 117x
Sell: 0x
Shares Bought: 14,254,348
Shares Sold: 0
Share Difference: +14,254,348
Value Difference: -$270,037,989

Mirati Therapeutics, Inc.

Trading Symbol: MYG
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC:
Holdings: 141,244 shares
Latest Transaction: Nov 20 2017

Last 4 weeks trend: STRONG SELL
Last 3 months trend: STRONG SELL View transactions

Last 3 Months Overview:
Buy: 7x
Sell: 12x
Shares Bought: 594,019
Shares Sold: 999,358
Share Difference: -405,339
Value Difference: +$5,084,890

Neoleukin Therapeutics, Inc.

Trading Symbol: NLTX
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: Director, 10% Owner
Holdings: 320,049 shares
Current Value: $6,020,122
Latest Transaction: Dec 23 2020
$NLTX Market Capitalization: $451.60M
$NLTX Previous Close: $18.81

Last 4 weeks trend: SELL
Last 3 months trend: SELL View transactions

Last 3 Months Overview:
Buy: 47x
Sell: 2x
Shares Bought: 7,466,401
Shares Sold: 10,925,481
Share Difference: -3,459,080
Value Difference: -$77,646,868

Prelude Therapeutics Inc

Trading Symbol: PRLD
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 876,061 shares
Latest Transaction: Jan 29 2021

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 10x
Sell: 0x
Shares Bought: 9,922,101
Shares Sold: 0
Share Difference: +9,922,101
Value Difference: -$30,133,324

RHYTHM PHARMACEUTICALS, INC.

Trading Symbol: RYTM
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC:
Holdings: 82,969 shares
Latest Transaction: Oct 06 2017

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 4x
Sell: 0x
Shares Bought: 2,049,020
Shares Sold: 0
Share Difference: +2,049,020
Value Difference: -$15,045,000

Seagen Inc.

Trading Symbol: SGEN
Industry: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 4,082,851 shares
Current Value: $248,196,512
Latest Transaction: May 19 2020
$SGEN Market Capitalization: $8.71B
$SGEN Previous Close: $60.79

Last 4 weeks trend: BUY
Last 3 months trend: BUY View transactions

Last 3 Months Overview:
Buy: 38x
Sell: 21x
Shares Bought: 5,573,658
Shares Sold: 3,810,799
Share Difference: +1,762,859
Value Difference: +$173,528,940

Talis Biomedical Corp

Trading Symbol: TLIS
Industry: LABORATORY ANALYTICAL INSTRUMENTS [3826]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 571,659 shares
Latest Transaction: Feb 19 2021

Last 4 weeks trend: STRONG BUY
Last 3 months trend: STRONG BUY View transactions

Last 3 Months Overview:
Buy: 2x
Sell: 0x
Shares Bought: 6,250,000
Shares Sold: 0
Share Difference: +6,250,000
Value Difference: -$100,000,000

XOMA Corp

Trading Symbol: XOMA
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC:
Holdings: 90,538 shares
Current Value: $381,165
Latest Transaction: Jul 23 2015
$XOMA Market Capitalization: $25.10M
$XOMA Previous Close: $4.21

Last 4 weeks trend: HOLD
Last 3 months trend: HOLD View transactions

Zymeworks Inc.

Trading Symbol: ZYME
Industry: PHARMACEUTICAL PREPARATIONS [2834]
Position of BAKER BROS ADVISORS LLC: Director
Holdings: 0 shares
Latest Transaction: May 12 2020

Last 4 weeks trend: HOLD
Last 3 months trend: HOLD View transactions

Latest Insider Trading Transactions of BAKER BROS ADVISORS LLC

Sentiment: All, ACAD, AGLE, ALXN, BCEL, BGNE, BLCM, BCRX, GHDX, HOOK, IDRA, IGMS, INCY, NTLA, NVTA, KNSA, KOD, MYG, NLTX, PRLD, RYTM, SGEN, TLIS, XOMA, ZYME

DateTickerCompanyOwnerRelationship Transaction Code Cost ($) Shares Transaction Value ($) Total Shares % Holdings
Feb 25 2021AGLEAeglea BioTherapeu ...BAKER BROS. ADVISORS LPDirectorOption ExerciseA7.1147,200335,59247,200
Feb 23 2021IGMSIGM Biosciences, I ...BAKER BROS. ADVISORS LPDirectorOption ExerciseA91.506,423587,7056,423
Feb 19 2021TLISTalis Biomedical C ...BAKER BROS. ADVISORS LPDirectorOption ExerciseM0.006,427,576027,511,741
Feb 19 2021TLISTalis Biomedical C ...BAKER BROS. ADVISORS LPDirectorOption ExerciseM0.00536,43802,345,481
Feb 19 2021TLISTalis Biomedical C ...BAKER BROS. ADVISORS LPDirectorOption ExerciseM0.007,286,794021,084,165
Feb 19 2021TLISTalis Biomedical C ...BAKER BROS. ADVISORS LPDirectorOption ExerciseM0.00536,41401,809,043
Feb 19 2021TLISTalis Biomedical C ...BAKER BROS. ADVISORS LPDirectorOption ExerciseM0.001,94105,420

View all BAKER BROS ADVISORS LLC insider transactions.