ORBIMED ADVISORS LLC Insider Trading for October 2015

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General | Insider Transactions | Monthly Overview

Overview of insider trading of ORBIMED ADVISORS LLC for October 2015.

Date	Ticker	Company	Owner	Relationship	Transaction	Code	Cost ($)	Shares	Transaction Value ($)	Total Shares	% Holdings
Oct 29 2015	DMTX	Dimension Therapeu ...	ORBIMED ADVISORS LLC	Director	Option Exercise	C	0.00	5,692,874	0	0
Oct 29 2015	DMTX	Dimension Therapeu ...	ORBIMED ADVISORS LLC	Director	Option Exercise	C	0.00	9,500,000	0	0
Oct 29 2015	DMTX	Dimension Therapeu ...	ORBIMED ADVISORS LLC	Director	Buy	P	13.00	200,000	2,600,000	5,397,698	5.2 M to 5.4 M (+3.85 %)
Oct 29 2015	DMTX	Dimension Therapeu ...	ORBIMED ADVISORS LLC	Director	Buy	C	0.00	1,947,613	0	5,197,698	3.3 M to 5.2 M (+59.92 %)
Oct 29 2015	DMTX	Dimension Therapeu ...	ORBIMED ADVISORS LLC	Director	Buy	C	0.00	3,250,085	0	3,250,085	0 to 3.3 M
Oct 22 2015	RLYP	Relypsa Inc	ORBIMED ADVISORS LLC	10% Owner	Buy	P	12.92	310,700	4,014,244	7,900,000	7.6 M to 7.9 M (+4.09 %)
Oct 22 2015	RLYP	Relypsa Inc	ORBIMED ADVISORS LLC	10% Owner	Buy	P	11.97	189,300	2,265,921	7,589,300	7.4 M to 7.6 M (+2.56 %)
Oct 13 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	5.98	2,785	16,654	17,100	19.9 K to 17.1 K (-14.01 %)
Oct 13 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	5.98	285,106	1,704,934	1,767,902	2.1 M to 1.8 M (-13.89 %)
Oct 09 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	7.03	2,041	14,348	19,885	21.9 K to 19.9 K (-9.31 %)
Oct 09 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	7.03	210,668	1,480,996	2,053,008	2.3 M to 2.1 M (-9.31 %)
Oct 09 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	7.24	3,837	27,780	21,926	25.8 K to 21.9 K (-14.89 %)
Oct 09 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	7.24	396,163	2,868,220	2,263,676	2.7 M to 2.3 M (-14.89 %)
Oct 09 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	7.36	454	3,341	25,763	26.2 K to 25.8 K (-1.73 %)
Oct 09 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	7.36	53,446	393,363	2,659,839	2.7 M to 2.7 M (-1.97 %)
Oct 06 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	7.80	59	460	26,217	26.3 K to 26.2 K (-0.22 %)
Oct 06 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	7.80	6,941	54,140	2,713,285	2.7 M to 2.7 M (-0.26 %)
Oct 06 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	8.19	1,163	9,525	26,276	27.4 K to 26.3 K (-4.24 %)
Oct 06 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	8.19	136,937	1,121,514	2,720,226	2.9 M to 2.7 M (-4.79 %)
Oct 06 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	10.34	403	4,167	27,439	27.8 K to 27.4 K (-1.45 %)
Oct 06 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	10.34	47,497	491,119	2,857,163	2.9 M to 2.9 M (-1.64 %)
Oct 01 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	10.34	400	4,136	27,842	28.2 K to 27.8 K (-1.42 %)
Oct 01 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	10.34	47,100	487,014	2,904,660	3 M to 2.9 M (-1.60 %)
Oct 01 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	10.17	369	3,753	28,242	28.6 K to 28.2 K (-1.29 %)
Oct 01 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	10.17	43,471	442,100	2,951,760	3 M to 3 M (-1.45 %)
Oct 01 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	10.08	89	897	28,611	28.7 K to 28.6 K (-0.31 %)
Oct 01 2015	SIEN	Sientra, Inc.	ORBIMED ADVISORS LLC	10% Owner	Sell	S	10.08	10,469	105,528	2,995,231	3 M to 3 M (-0.35 %)