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General | Insiders | Insider Transactions | Monthly Overview | Weekly Overview

Overview of all insider trading transactions in Karyopharm Therapeutics Inc.. Get notifications about new insider transactions in Karyopharm Therapeutics Inc. for free.

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Date	Ticker	Company	Owner	Relationship	Transaction	Code	Cost ($)	Shares	Transaction Value ($)	Total Shares	% Holdings
Jan 09 2018	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Buy	M	0.26	10,000	2,640	723,510	713.5 K to 723.5 K (+1.40 %)
Dec 20 2017	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Option Exercise	M	0.26	10,000	2,640	32,424
Dec 20 2017	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Sell	S	9.16	10,000	91,553	512,143	522.1 K to 512.1 K (-1.92 %)
Dec 20 2017	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Buy	M	0.26	10,000	2,640	522,143	512.1 K to 522.1 K (+1.95 %)
Dec 20 2017	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Option Exercise	M	0.26	10,000	2,640	32,424
Dec 20 2017	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Sell	S	9.16	10,000	91,553	512,143	522.1 K to 512.1 K (-1.92 %)
Dec 20 2017	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Buy	M	0.26	10,000	2,640	522,143	512.1 K to 522.1 K (+1.95 %)
Dec 13 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Option Exercise	M	6.54	17,000	111,180	23,000
Dec 13 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Sell	S	9.59	644	6,173	11,381	12 K to 11.4 K (-5.36 %)
Dec 13 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Sell	S	9.93	16,356	162,443	12,025	28.4 K to 12 K (-57.63 %)
Dec 13 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Buy	M	6.54	17,000	111,180	28,381	11.4 K to 28.4 K (+149.37 %)
Dec 13 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Sell	S	10.88	10,042	109,256	11,381	21.4 K to 11.4 K (-46.87 %)
Dec 08 2017	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Option Exercise	M	0.26	10,000	2,640	29,394
Dec 08 2017	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Sell	S	10.39	10,000	103,903	713,510	723.5 K to 713.5 K (-1.38 %)
Dec 08 2017	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Buy	M	0.26	10,000	2,640	723,510	713.5 K to 723.5 K (+1.40 %)
Dec 08 2017	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Option Exercise	M	0.26	10,000	2,640	29,394
Dec 08 2017	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Sell	S	10.39	10,000	103,903	713,510	723.5 K to 713.5 K (-1.38 %)
Dec 08 2017	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Buy	M	0.26	10,000	2,640	723,510	713.5 K to 723.5 K (+1.40 %)
Nov 09 2017	KPTI	Karyopharm Therape ...	Frenkel Ran	Chief Dev Operation ...	Sell	S	11.25	4,958	55,755	24,733	29.7 K to 24.7 K (-16.70 %)
Nov 09 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Sell	S	11.25	4,958	55,755	21,423	26.4 K to 21.4 K (-18.79 %)
Nov 06 2017	KPTI	Karyopharm Therape ...	Frenkel Ran	Chief Dev Operation ...	Option Exercise	M	0.00	15,000	0	0
Nov 06 2017	KPTI	Karyopharm Therape ...	Frenkel Ran	Chief Dev Operation ...	Buy	M	0.00	15,000	0	29,691	14.7 K to 29.7 K (+102.10 %)
Nov 06 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Option Exercise	M	0.00	15,000	0	0
Nov 06 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Buy	M	0.00	15,000	0	26,381	11.4 K to 26.4 K (+131.80 %)
Oct 04 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	M	0.26	2,000	528	1,099
Oct 04 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Sell	S	12.00	2,000	24,000	0	2 K to 0 (-100.00 %)
Oct 04 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Buy	M	0.26	2,000	528	2,000	0 to 2 K
Oct 04 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Sell	S	12.00	1,500	18,000	11,381	12.9 K to 11.4 K (-11.65 %)
Sep 18 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	M	0.26	2,882	761	3,099
Sep 18 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Sell	S	11.00	2,882	31,702	0	2.9 K to 0 (-100.00 %)
Sep 18 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Buy	M	0.26	2,882	761	2,882	0 to 2.9 K
Sep 18 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Sell	S	11.00	2,000	22,000	12,881	14.9 K to 12.9 K (-13.44 %)
Sep 13 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	M	0.26	118	31	5,981
Sep 13 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Sell	S	11.00	118	1,298	0	118 to 0 (-100.00 %)
Sep 13 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Buy	M	0.26	118	31	118	0 to 118
Sep 13 2017	KPTI	Karyopharm Therape ...	FALVEY MICHAEL	EVP, CFO & Treasure ...	Option Exercise	A	10.60	125,000	1,325,000	125,000
Sep 01 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Sell	S	10.03	805	8,071	14,881	15.7 K to 14.9 K (-5.13 %)
Aug 30 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Sell	S	10.00	2,195	21,950	15,686	17.9 K to 15.7 K (-12.28 %)
Jun 16 2017	KPTI	Karyopharm Therape ...	WEG KENNETH E	Director	Option Exercise	A	9.18	17,000	156,060	17,000
Jun 16 2017	KPTI	Karyopharm Therape ...	PAKIANATHAN DEEPIKA	Director	Option Exercise	A	9.18	17,000	156,060	17,000
Jun 16 2017	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	A	9.18	17,000	156,060	17,000
Jun 16 2017	KPTI	Karyopharm Therape ...	Greene Barry E	Director	Option Exercise	A	9.18	17,000	156,060	17,000
Jun 16 2017	KPTI	Karyopharm Therape ...	Garland J. Scott	Director	Option Exercise	A	9.18	17,000	156,060	17,000
Jun 16 2017	KPTI	Karyopharm Therape ...	Dolsten Mikael	Director	Option Exercise	A	9.18	17,000	156,060	17,000
Jun 16 2017	KPTI	Karyopharm Therape ...	BOHLIN GAREN G	Director	Option Exercise	A	9.18	17,000	156,060	17,000
Jan 24 2017	KPTI	Karyopharm Therape ...	Frenkel Ran	Chief Dev Operation ...	Option Exercise	A	10.39	100,000	1,039,000	100,000
Jan 24 2017	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP, OPS, BUS DEV, ...	Option Exercise	A	10.39	118,000	1,226,020	118,000
Jan 24 2017	KPTI	Karyopharm Therape ...	Renz Justin A	EVP, CFO & Treasure ...	Option Exercise	A	10.39	100,000	1,039,000	100,000
Jan 24 2017	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Option Exercise	A	10.39	250,000	2,597,500	250,000
Jan 24 2017	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Option Exercise	A	10.39	250,000	2,597,500	250,000
Jan 24 2017	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Option Exercise	A	10.39	250,000	2,597,500	250,000
Jan 24 2017	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Option Exercise	A	10.39	250,000	2,597,500	250,000
Nov 15 2016	KPTI	Karyopharm Therape ...	Frenkel Ran	Chief Dev Operation ...	Sell	S	10.06	3,309	33,286	14,691	18 K to 14.7 K (-18.38 %)
Nov 14 2016	KPTI	Karyopharm Therape ...	Renz Justin A	EVP, CFO & Treasure ...	Sell	S	8.19	4,342	35,544	19,173	23.5 K to 19.2 K (-18.46 %)
Nov 14 2016	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP,CORP DEV,GEN CO ...	Sell	S	8.19	4,342	35,544	15,819	20.2 K to 15.8 K (-21.54 %)
Nov 08 2016	KPTI	Karyopharm Therape ...	Frenkel Ran	Chief Dev Operation ...	Option Exercise	M	0.00	15,000	0	15,000
Nov 08 2016	KPTI	Karyopharm Therape ...	Frenkel Ran	Chief Dev Operation ...	Buy	M	0.00	15,000	0	18,000	3 K to 18 K (+500.00 %)
Nov 08 2016	KPTI	Karyopharm Therape ...	Renz Justin A	EVP, CFO & Treasure ...	Option Exercise	M	0.00	15,000	0	15,000
Nov 08 2016	KPTI	Karyopharm Therape ...	Renz Justin A	EVP, CFO & Treasure ...	Buy	M	0.00	15,000	0	23,515	8.5 K to 23.5 K (+176.16 %)
Nov 08 2016	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP,CORP DEV,GEN CO ...	Option Exercise	M	0.00	15,000	0	15,000
Nov 08 2016	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP,CORP DEV,GEN CO ...	Buy	M	0.00	15,000	0	20,161	5.2 K to 20.2 K (+290.64 %)
Jun 27 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.03	18,824	151,083	8,549,920	8.6 M to 8.5 M (-0.22 %)
Jun 17 2016	KPTI	Karyopharm Therape ...	WEG KENNETH E	Director	Option Exercise	A	8.06	10,000	80,600	10,000
Jun 17 2016	KPTI	Karyopharm Therape ...	PAKIANATHAN DEEPIKA	Director	Option Exercise	A	8.06	10,000	80,600	10,000
Jun 17 2016	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	A	8.06	10,000	80,600	10,000
Jun 17 2016	KPTI	Karyopharm Therape ...	Greene Barry E	Director	Option Exercise	A	8.06	10,000	80,600	10,000
Jun 17 2016	KPTI	Karyopharm Therape ...	Garland J. Scott	Director	Option Exercise	A	8.06	10,000	80,600	10,000
Jun 17 2016	KPTI	Karyopharm Therape ...	Dolsten Mikael	Director	Option Exercise	A	8.06	10,000	80,600	10,000
Jun 17 2016	KPTI	Karyopharm Therape ...	BOHLIN GAREN G	Director	Option Exercise	A	8.06	10,000	80,600	10,000
Jun 15 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.51	7,074	60,214	8,568,744	8.6 M to 8.6 M (-0.08 %)
Jun 10 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.14	30,000	274,098	8,575,818	8.6 M to 8.6 M (-0.35 %)
Jun 10 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.34	15,541	145,186	8,605,818	8.6 M to 8.6 M (-0.18 %)
Jun 08 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.25	20,000	185,086	8,621,359	8.6 M to 8.6 M (-0.23 %)
Jun 08 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.22	20,000	184,464	8,641,359	8.7 M to 8.6 M (-0.23 %)
Jun 06 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.65	17,855	172,244	8,661,359	8.7 M to 8.7 M (-0.21 %)
Jun 01 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.64	17,568	169,327	8,679,214	8.7 M to 8.7 M (-0.20 %)
Jun 01 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.66	17,096	165,072	8,696,782	8.7 M to 8.7 M (-0.20 %)
Jun 01 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.58	40,000	383,200	8,713,878	8.8 M to 8.7 M (-0.46 %)
May 27 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.59	18,182	174,287	8,753,878	8.8 M to 8.8 M (-0.21 %)
May 27 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	9.83	27,940	274,541	8,772,060	8.8 M to 8.8 M (-0.32 %)
May 23 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.77	33,932	297,414	8,800,000	8.8 M to 8.8 M (-0.38 %)
May 23 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.52	40,000	340,748	8,833,932	8.9 M to 8.8 M (-0.45 %)
May 23 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.18	20,000	163,644	8,873,932	8.9 M to 8.9 M (-0.22 %)
May 19 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.15	30,000	244,488	8,893,932	8.9 M to 8.9 M (-0.34 %)
May 19 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.15	33,800	275,480	8,923,932	9 M to 8.9 M (-0.38 %)
May 17 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.01	10,000	80,065	8,957,732	9 M to 9 M (-0.11 %)
May 17 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.01	400	3,203	8,967,732	9 M to 9 M (0.00 %)
May 12 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.41	11,868	99,860	8,968,132	9 M to 9 M (-0.13 %)
May 12 2016	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	8.14	20,000	162,788	8,980,000	9 M to 9 M (-0.22 %)
Jan 20 2016	KPTI	Karyopharm Therape ...	Frenkel Ran	Chief Dev Operation ...	Option Exercise	A	6.54	75,000	490,500	75,000
Jan 20 2016	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP,CORP DEV,GEN CO ...	Option Exercise	A	6.54	40,000	261,600	40,000
Jan 20 2016	KPTI	Karyopharm Therape ...	Renz Justin A	EVP, CFO & Treasure ...	Option Exercise	A	6.54	100,000	654,000	100,000
Jan 20 2016	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Option Exercise	A	6.54	170,000	1,111,800	170,000
Jan 20 2016	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Option Exercise	A	6.54	170,000	1,111,800	170,000
Jan 20 2016	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Option Exercise	A	6.54	170,000	1,111,800	170,000
Jan 20 2016	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Option Exercise	A	6.54	170,000	1,111,800	170,000
Dec 10 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	M	0.26	2,121	560	6,099
Dec 10 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	M	0.03	6,061	200	0
Dec 10 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	M	0.03	2,556	84	0
Dec 10 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Sell	S	15.01	6,383	95,803	0	6.4 K to 0 (-100.00 %)
Dec 10 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Buy	M	0.26	2,121	560	6,383	4.3 K to 6.4 K (+49.77 %)
Dec 10 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Sell	S	15.01	6,061	90,970	4,262	10.3 K to 4.3 K (-58.71 %)
Dec 10 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Buy	M	0.03	6,061	200	10,323	4.3 K to 10.3 K (+142.21 %)
Dec 10 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Sell	S	15.01	2,556	38,363	4,262	6.8 K to 4.3 K (-37.49 %)
Dec 10 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Buy	M	0.03	2,556	84	6,818	4.3 K to 6.8 K (+59.97 %)
Nov 09 2015	KPTI	Karyopharm Therape ...	Frenkel Ran	EVP, WW Development ...	Option Exercise	A	0.00	30,000	0	30,000
Nov 09 2015	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP,CORP DEV,GEN CO ...	Option Exercise	A	0.00	30,000	0	30,000
Nov 09 2015	KPTI	Karyopharm Therape ...	Renz Justin A	EVP, CFO & Treasure ...	Option Exercise	A	0.00	30,000	0	30,000
Sep 21 2015	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	SVP,CORP DEV,GEN CO ...	Option Exercise	A	14.94	75,000	1,120,500	75,000
May 26 2015	KPTI	Karyopharm Therape ...	WEG KENNETH E	Director	Option Exercise	A	26.15	10,000	261,500	10,000
May 26 2015	KPTI	Karyopharm Therape ...	PAKIANATHAN DEEPIKA	Director	Option Exercise	A	26.15	10,000	261,500	10,000
May 26 2015	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	A	26.15	10,000	261,500	10,000
May 26 2015	KPTI	Karyopharm Therape ...	Greene Barry E	Director	Option Exercise	A	26.15	10,000	261,500	10,000
May 26 2015	KPTI	Karyopharm Therape ...	Garland J. Scott	Director	Option Exercise	A	26.15	10,000	261,500	10,000
May 26 2015	KPTI	Karyopharm Therape ...	Dolsten Mikael	Director	Option Exercise	A	26.15	10,000	261,500	10,000
May 26 2015	KPTI	Karyopharm Therape ...	BOHLIN GAREN G	Director	Option Exercise	A	26.15	10,000	261,500	10,000
Apr 08 2015	KPTI	Karyopharm Therape ...	Frenkel Ran	EVP, WW Development ...	Buy	P	33.00	2,000	66,000	3,000	1,000 to 3 K (+200.00 %)
Apr 08 2015	KPTI	Karyopharm Therape ...	Frenkel Ran	EVP, WW Development ...	Buy	P	29.43	1,000	29,430	1,000	0 to 1,000
Apr 06 2015	KPTI	Karyopharm Therape ...	Greene Barry E	Director	Buy	P	29.31	3,000	87,938	3,000	0 to 3 K
Apr 06 2015	KPTI	Karyopharm Therape ...	Renz Justin A	EVP, CFO & Treasure ...	Buy	P	29.71	5,000	148,557	5,000	0 to 5 K
Apr 06 2015	KPTI	Karyopharm Therape ...	WEG KENNETH E	Director	Grant	A	29.55	5,000	147,760	5,000	0 to 5 K
Apr 02 2015	KPTI	Karyopharm Therape ...	Dolsten Mikael	Director	Option Exercise	A	30.61	20,000	612,200	20,000
Jan 22 2015	KPTI	Karyopharm Therape ...	Primiano Christopher Brett	VP, GEN COUNSEL & S ...	Option Exercise	A	26.65	125,000	3,331,250	125,000
Jan 22 2015	KPTI	Karyopharm Therape ...	Renz Justin A	EVP, CFO & Treasure ...	Option Exercise	A	26.65	45,000	1,199,250	45,000
Jan 22 2015	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Option Exercise	A	26.65	200,000	5,330,000	200,000
Jan 22 2015	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Option Exercise	A	26.65	200,000	5,330,000	200,000
Jan 22 2015	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Option Exercise	A	26.65	200,000	5,330,000	200,000
Jan 22 2015	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Option Exercise	A	26.65	200,000	5,330,000	200,000
Jan 14 2015	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Sell	S	33.00	25,000	825,000	562,596	587.6 K to 562.6 K (-4.25 %)
Jan 14 2015	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Sell	S	33.00	25,000	825,000	763,963	789 K to 764 K (-3.17 %)
Jan 14 2015	KPTI	Karyopharm Therape ...	Shacham Sharon	President & CSO	Gift	G	0.00	20,000	0	788,963	809 K to 789 K (-2.47 %)
Jan 14 2015	KPTI	Karyopharm Therape ...	PAKIANATHAN DEEPIKA	Director	Buy	P	33.00	440	14,520	21,883	21.4 K to 21.9 K (+2.05 %)
Jan 14 2015	KPTI	Karyopharm Therape ...	PAKIANATHAN DEEPIKA	Director	Buy	P	33.00	45,014	1,485,462	2,241,123	2.2 M to 2.2 M (+2.05 %)
Jan 14 2015	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Sell	S	33.00	25,000	825,000	763,963	789 K to 764 K (-3.17 %)
Jan 14 2015	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Sell	S	33.00	25,000	825,000	562,596	587.6 K to 562.6 K (-4.25 %)
Jan 14 2015	KPTI	Karyopharm Therape ...	Kauffman Michael	Chief Executive Off ...	Gift	G	0.00	20,000	0	788,963	809 K to 789 K (-2.47 %)
Dec 03 2014	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	M	0.03	5,000	165	2,555
Dec 03 2014	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Option Exercise	M	0.03	1,535	51	7,555
Dec 03 2014	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Sell	S	45.18	5,000	225,881	4,262	9.3 K to 4.3 K (-53.98 %)
Dec 03 2014	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Buy	M	0.03	5,000	165	9,262	4.3 K to 9.3 K (+117.32 %)
Dec 03 2014	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Sell	S	41.86	5,000	209,286	4,262	9.3 K to 4.3 K (-53.98 %)
Dec 03 2014	KPTI	Karyopharm Therape ...	Mirza Mansoor Raza	Director	Buy	M	0.03	1,535	51	9,262	7.7 K to 9.3 K (+19.87 %)
Dec 01 2014	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	41.76	198,115	8,273,223	9,132,700	9.3 M to 9.1 M (-2.12 %)
Dec 01 2014	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	42.18	25,000	1,054,520	9,330,815	9.4 M to 9.3 M (-0.27 %)
Dec 01 2014	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	42.74	4,094	174,992	9,355,815	9.4 M to 9.4 M (-0.04 %)
Dec 01 2014	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	42.35	50,906	2,155,925	9,360	60.3 K to 9.4 K (-84.47 %)
Nov 25 2014	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	44.03	10,501	462,410	9,410,815	9.4 M to 9.4 M (-0.11 %)
Nov 25 2014	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	43.54	61,326	2,670,373	9,421,316	9.5 M to 9.4 M (-0.65 %)
Nov 25 2014	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	42.51	53,173	2,260,320	9,482,642	9.5 M to 9.5 M (-0.56 %)
Nov 25 2014	KPTI	Karyopharm Therape ...	Chione Ltd	10% Owner	Sell	S	41.78	75,000	3,133,800	9,535,815	9.6 M to 9.5 M (-0.78 %)

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