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General | Insiders | Insider Transactions | Monthly Overview | Weekly Overview

Overview of all insider trading transactions in MEDICINES CO /DE. Get notifications about new insider transactions in MEDICINES CO /DE for free.

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Date	Ticker	Company	Owner	Relationship	Transaction	Code	Cost ($)	Shares	Transaction Value ($)	Total Shares	% Holdings
Dec 31 2019	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Buy	M	7.31	7,500	54,825	36,707	29.2 K to 36.7 K (+25.68 %)
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Option Exercise	M	30.55	11,483	350,806	120,000
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Option Exercise	M	31.49	64,568	2,033,246	0
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Option Exercise	M	22.04	150,000	3,306,000	0
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Option Exercise	M	17.45	240,000	4,188,000	0
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Option Exercise	M	13.54	15,620	211,495	0
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Option Exercise	M	7.31	60,000	438,600	0
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Payment of Exercise	F	84.78	22,345	1,894,409	480,340	502.7 K to 480.3 K (-4.45 %)
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Payment of Exercise	F	84.78	329,796	27,960,105	502,685	832.5 K to 502.7 K (-39.62 %)
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Buy	M	30.55	11,483	350,806	832,481	821 K to 832.5 K (+1.40 %)
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Buy	M	31.49	64,568	2,033,246	820,998	756.4 K to 821 K (+8.54 %)
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Buy	M	22.04	150,000	3,306,000	756,430	606.4 K to 756.4 K (+24.73 %)
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Buy	M	17.45	240,000	4,188,000	606,430	366.4 K to 606.4 K (+65.50 %)
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Buy	M	13.54	15,620	211,495	366,430	350.8 K to 366.4 K (+4.45 %)
Dec 31 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Buy	M	7.31	60,000	438,600	350,810	290.8 K to 350.8 K (+20.63 %)
Sep 04 2019	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Grant	A	21.60	491	10,606	28,630	28.1 K to 28.6 K (+1.74 %)
Sep 04 2019	MDCO	MEDICINES CO /DE	Timney Mark	Chief Executive Off ...	Grant	A	21.60	491	10,606	30,280	29.8 K to 30.3 K (+1.65 %)
Sep 04 2019	MDCO	MEDICINES CO /DE	Wijngaard Peter	Chief Development O ...	Grant	A	21.60	491	10,606	2,448	2 K to 2.4 K (+25.09 %)
Sep 04 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Grant	A	21.60	491	10,606	290,810	290.3 K to 290.8 K (+0.17 %)
Aug 06 2019	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Option Exercise	M	8.38	5,000	41,900	0
Aug 06 2019	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Sell	S	34.82	5,000	174,100	28,139	33.1 K to 28.1 K (-15.09 %)
Aug 06 2019	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Buy	M	8.38	5,000	41,900	33,139	28.1 K to 33.1 K (+17.77 %)
Jun 28 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	33.00	50,000	1,650,000	4,202,000	4.2 M to 4.2 M (+1.20 %)
Jun 28 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	33.00	50,000	1,650,000	4,202,000	4.2 M to 4.2 M (+1.20 %)
Jun 03 2019	MDCO	MEDICINES CO /DE	Germano Geno J	Director	Option Exercise	A	34.81	8,410	292,752	8,410
Jun 03 2019	MDCO	MEDICINES CO /DE	Germano Geno J	Director	Grant	A	0.00	3,663	0	7,429	3.8 K to 7.4 K (+97.27 %)
Jun 03 2019	MDCO	MEDICINES CO /DE	Kelly John C.	Director	Option Exercise	A	34.81	8,410	292,752	8,410
Jun 03 2019	MDCO	MEDICINES CO /DE	Kelly John C.	Director	Grant	A	0.00	3,663	0	32,148	28.5 K to 32.1 K (+12.86 %)
Jun 03 2019	MDCO	MEDICINES CO /DE	Panayiotopoulos Paris	Director	Option Exercise	A	34.81	8,410	292,752	8,410
Jun 03 2019	MDCO	MEDICINES CO /DE	Panayiotopoulos Paris	Director	Grant	A	0.00	3,663	0	13,881	10.2 K to 13.9 K (+35.85 %)
Jun 03 2019	MDCO	MEDICINES CO /DE	Schlesinger Sarah J.	Director	Option Exercise	A	34.81	8,410	292,752	8,410
Jun 03 2019	MDCO	MEDICINES CO /DE	Schlesinger Sarah J.	Director	Grant	A	0.00	3,663	0	7,429	3.8 K to 7.4 K (+97.27 %)
Jun 03 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Option Exercise	A	34.81	13,410	466,802	13,410
Jun 03 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Grant	A	0.00	3,663	0	14,092	10.4 K to 14.1 K (+35.12 %)
May 31 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	34.81	50,000	1,740,500	4,152,000	4.1 M to 4.2 M (+1.22 %)
May 31 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	34.85	35,000	1,219,750	4,102,000	4.1 M to 4.1 M (+0.86 %)
May 22 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	33.13	139,000	4,605,070	4,067,000	3.9 M to 4.1 M (+3.54 %)
May 22 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	33.95	132,000	4,481,400	3,928,000	3.8 M to 3.9 M (+3.48 %)
May 22 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	34.50	160,000	5,520,000	3,796,000	3.6 M to 3.8 M (+4.40 %)
Apr 26 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Payment of Exercise	F	30.48	2,796	85,222	290,319	293.1 K to 290.3 K (-0.95 %)
Mar 08 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	24.91	248,100	6,180,171	3,636,000	3.4 M to 3.6 M (+7.32 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Payment of Exercise	F	25.53	476	12,152	28,139	28.6 K to 28.1 K (-1.66 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Payment of Exercise	F	25.53	527	13,454	28,615	29.1 K to 28.6 K (-1.81 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Payment of Exercise	F	25.53	671	17,131	29,142	29.8 K to 29.1 K (-2.25 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Payment of Exercise	F	25.53	78	1,991	29,813	29.9 K to 29.8 K (-0.26 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Visioli Christopher	Chief Financial Off ...	Payment of Exercise	F	25.53	381	9,727	7,252	7.6 K to 7.3 K (-4.99 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Visioli Christopher	Chief Financial Off ...	Payment of Exercise	F	25.53	238	6,076	7,633	7.9 K to 7.6 K (-3.02 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Visioli Christopher	Chief Financial Off ...	Payment of Exercise	F	25.53	212	5,412	7,871	8.1 K to 7.9 K (-2.62 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Visioli Christopher	Chief Financial Off ...	Payment of Exercise	F	25.53	78	1,991	8,083	8.2 K to 8.1 K (-0.96 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Payment of Exercise	F	25.53	2,962	75,620	293,115	296.1 K to 293.1 K (-1.00 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Payment of Exercise	F	25.53	3,586	91,551	296,077	299.7 K to 296.1 K (-1.20 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Payment of Exercise	F	25.53	3,063	78,198	299,663	302.7 K to 299.7 K (-1.01 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Cox Christopher T	EVP & Chief Corp. D ...	Payment of Exercise	F	25.53	1,436	36,661	57,987	59.4 K to 58 K (-2.42 %)
Mar 06 2019	MDCO	MEDICINES CO /DE	Cox Christopher T	EVP & Chief Corp. D ...	Payment of Exercise	F	25.53	1,202	30,687	59,423	60.6 K to 59.4 K (-1.98 %)
Mar 05 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	26.07	181,900	4,742,133	3,387,900	3.2 M to 3.4 M (+5.67 %)
Mar 05 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	25.45	325,000	8,271,250	3,206,000	2.9 M to 3.2 M (+11.28 %)
Mar 05 2019	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	25.15	100,000	2,515,000	2,881,000	2.8 M to 2.9 M (+3.60 %)
Mar 04 2019	MDCO	MEDICINES CO /DE	Cox Christopher T	EVP & Chief Corp. D ...	Grant	A	20.97	317	6,647	60,625	60.3 K to 60.6 K (+0.53 %)
Mar 04 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Option Exercise	A	25.41	95,000	2,413,950	95,000
Mar 04 2019	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	Chief Innovation Of ...	Grant	A	20.97	317	6,647	302,726	302.4 K to 302.7 K (+0.10 %)
Mar 04 2019	MDCO	MEDICINES CO /DE	Visioli Christopher	Chief Financial Off ...	Option Exercise	A	25.41	65,000	1,651,650	65,000
Dec 27 2018	MDCO	MEDICINES CO /DE	Timney Mark	Chief Executive Off ...	Buy	P	17.90	2,926	52,375	29,789	26.9 K to 29.8 K (+10.89 %)
Dec 21 2018	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	17.89	10,000	178,900	2,781,000	2.8 M to 2.8 M (+0.36 %)
Dec 21 2018	MDCO	MEDICINES CO /DE	Cox Christopher T	EVP & Chief Corp. D ...	Buy	P	17.70	113,500	2,008,950	334,955	221.5 K to 335 K (+51.25 %)
Dec 18 2018	MDCO	MEDICINES CO /DE	Timney Mark	Chief Executive Off ...	Option Exercise	A	20.79	450,000	9,355,500	450,000
Dec 18 2018	MDCO	MEDICINES CO /DE	Timney Mark	Chief Executive Off ...	Buy	P	18.60	26,863	499,652	26,863	0 to 26.9 K
Dec 18 2018	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	18.18	10,000	181,800	2,771,000	2.8 M to 2.8 M (+0.36 %)
Dec 18 2018	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	17.91	20,000	358,200	2,761,000	2.7 M to 2.8 M (+0.73 %)
Dec 17 2018	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	18.97	219,000	4,154,430	2,741,000	2.5 M to 2.7 M (+8.68 %)
Dec 17 2018	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	20.73	600,000	12,438,000	2,522,000	1.9 M to 2.5 M (+31.22 %)
Nov 19 2018	MDCO	MEDICINES CO /DE	Cox Christopher T	EVP & Chief Corp. D ...	Buy	P	19.73	50,300	992,419	221,455	171.2 K to 221.5 K (+29.39 %)
Sep 05 2018	MDCO	MEDICINES CO /DE	Cox Christopher T	EVP & Chief Corp. D ...	Grant	A	28.28	375	10,605	60,308	59.9 K to 60.3 K (+0.63 %)
Sep 05 2018	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Sell	S	39.31	50,000	1,965,500	302,409	352.4 K to 302.4 K (-14.19 %)
Sep 05 2018	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Grant	A	28.28	375	10,605	352,409	352 K to 352.4 K (+0.11 %)
Sep 05 2018	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Grant	A	28.28	375	10,605	29,574	29.2 K to 29.6 K (+1.28 %)
Aug 02 2018	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Sell	S	39.24	50,000	1,962,000	352,034	402 K to 352 K (-12.44 %)
Jul 05 2018	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Sell	S	36.07	50,000	1,803,500	402,034	452 K to 402 K (-11.06 %)
Jun 04 2018	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Option Exercise	A	33.86	9,141	309,514	9,141
Jun 04 2018	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Grant	A	0.00	3,766	0	10,429	6.7 K to 10.4 K (+56.52 %)
Jun 04 2018	MDCO	MEDICINES CO /DE	ESHELMAN FREDRIC N	Executive Chairman	Option Exercise	A	33.86	14,141	478,814	14,141
Jun 04 2018	MDCO	MEDICINES CO /DE	ESHELMAN FREDRIC N	Executive Chairman	Grant	A	0.00	3,766	0	1,132,149	1.1 M to 1.1 M (+0.33 %)
Jun 04 2018	MDCO	MEDICINES CO /DE	Schlesinger Sarah J.	Director	Option Exercise	A	33.86	9,141	309,514	9,141
Jun 04 2018	MDCO	MEDICINES CO /DE	Schlesinger Sarah J.	Director	Grant	A	0.00	3,766	0	3,766	0 to 3.8 K
Jun 04 2018	MDCO	MEDICINES CO /DE	Panayiotopoulos Paris	Director	Option Exercise	A	33.86	9,141	309,514	9,141
Jun 04 2018	MDCO	MEDICINES CO /DE	Panayiotopoulos Paris	Director	Grant	A	0.00	3,766	0	10,218	6.5 K to 10.2 K (+58.37 %)
Jun 04 2018	MDCO	MEDICINES CO /DE	Germano Geno J	Director	Option Exercise	A	33.86	9,141	309,514	9,141
Jun 04 2018	MDCO	MEDICINES CO /DE	Germano Geno J	Director	Grant	A	0.00	3,766	0	3,766	0 to 3.8 K
Jun 04 2018	MDCO	MEDICINES CO /DE	Kelly John C.	Director	Option Exercise	A	33.86	9,141	309,514	9,141
Jun 04 2018	MDCO	MEDICINES CO /DE	Kelly John C.	Director	Grant	A	0.00	3,766	0	28,485	24.7 K to 28.5 K (+15.24 %)
May 29 2018	MDCO	MEDICINES CO /DE	Spigelman Melvin K	Director	Option Exercise	M	18.30	7,500	137,250	0
May 29 2018	MDCO	MEDICINES CO /DE	Spigelman Melvin K	Director	Sell	S	32.20	7,500	241,500	53,133	60.6 K to 53.1 K (-12.37 %)
May 29 2018	MDCO	MEDICINES CO /DE	Spigelman Melvin K	Director	Buy	M	18.30	7,500	137,250	60,633	53.1 K to 60.6 K (+14.12 %)
May 14 2018	MDCO	MEDICINES CO /DE	KESSLER ARMIN M	Director	Option Exercise	M	18.30	7,500	137,250	0
May 14 2018	MDCO	MEDICINES CO /DE	KESSLER ARMIN M	Director	Buy	M	18.30	7,500	137,250	138,493	131 K to 138.5 K (+5.73 %)
Apr 26 2018	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Grant	A	0.00	22,589	0	452,034	429.4 K to 452 K (+5.26 %)
Apr 18 2018	MDCO	MEDICINES CO /DE	KESSLER ARMIN M	Director	Sell	S	30.05	10,000	300,500	130,993	141 K to 131 K (-7.09 %)
Apr 18 2018	MDCO	MEDICINES CO /DE	KESSLER ARMIN M	Director	Sell	S	27.37	10,000	273,700	140,993	151 K to 141 K (-6.62 %)
Mar 23 2018	MDCO	MEDICINES CO /DE	WYATT ELIZABETH H S	Director	Option Exercise	M	18.30	7,500	137,250	0
Mar 23 2018	MDCO	MEDICINES CO /DE	WYATT ELIZABETH H S	Director	Buy	M	18.30	7,500	137,250	60,633	53.1 K to 60.6 K (+14.12 %)
Mar 23 2018	MDCO	MEDICINES CO /DE	CROUSE WILLIAM	Director	Option Exercise	M	18.30	7,500	137,250	0
Mar 23 2018	MDCO	MEDICINES CO /DE	CROUSE WILLIAM	Director	Sell	S	32.26	7,500	241,950	53,133	60.6 K to 53.1 K (-12.37 %)
Mar 23 2018	MDCO	MEDICINES CO /DE	CROUSE WILLIAM	Director	Buy	M	18.30	7,500	137,250	60,633	53.1 K to 60.6 K (+14.12 %)
Mar 02 2018	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Grant	A	0.00	6,250	0	30,511	24.3 K to 30.5 K (+25.76 %)
Mar 02 2018	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Grant	A	26.02	330	8,587	24,261	23.9 K to 24.3 K (+1.38 %)
Mar 02 2018	MDCO	MEDICINES CO /DE	O'Connor William Bernard	Chief Financial Off ...	Grant	A	26.02	330	8,587	24,545	24.2 K to 24.5 K (+1.36 %)
Mar 02 2018	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Grant	A	26.02	330	8,587	451,732	451.4 K to 451.7 K (+0.07 %)
Mar 02 2018	MDCO	MEDICINES CO /DE	Frazier Jeff	EVP, Chief Human St ...	Grant	A	26.02	330	8,587	35,776	35.4 K to 35.8 K (+0.93 %)
Mar 02 2018	MDCO	MEDICINES CO /DE	Cox Christopher T	EVP & Chief Corp. D ...	Grant	A	0.00	15,000	0	60,943	45.9 K to 60.9 K (+32.65 %)
Mar 02 2018	MDCO	MEDICINES CO /DE	Cox Christopher T	EVP & Chief Corp. D ...	Grant	A	26.02	330	8,587	45,943	45.6 K to 45.9 K (+0.72 %)
Feb 26 2018	MDCO	MEDICINES CO /DE	Schlesinger Sarah J.	Director	Option Exercise	A	29.83	26,383	787,005	26,383
Dec 19 2017	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Option Exercise	M	19.36	200,920	3,889,811	0
Dec 19 2017	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Sell	S	27.24	136,250	3,711,450	451,402	587.7 K to 451.4 K (-23.19 %)
Dec 19 2017	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Buy	M	19.36	200,920	3,889,811	587,652	386.7 K to 587.7 K (+51.95 %)
Dec 11 2017	MDCO	MEDICINES CO /DE	ESHELMAN FREDRIC N	Executive Chairman	Buy	P	26.65	100,000	2,665,000	1,128,383	1 M to 1.1 M (+9.72 %)
Dec 11 2017	MDCO	MEDICINES CO /DE	ESHELMAN FREDRIC N	Executive Chairman	Buy	P	26.46	100,000	2,646,000	1,028,383	928.4 K to 1 M (+10.77 %)
Dec 01 2017	MDCO	MEDICINES CO /DE	Panayiotopoulos Paris	Director	Buy	P	30.97	3,215	99,569	6,452	3.2 K to 6.5 K (+99.32 %)
Nov 30 2017	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Buy	P	30.03	170,000	5,105,100	1,922,000	1.8 M to 1.9 M (+9.70 %)
Nov 20 2017	MDCO	MEDICINES CO /DE	Germano Geno J	Director	Option Exercise	A	30.90	27,243	841,809	27,243
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Option Exercise	M	21.14	12,039	254,504	0
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Option Exercise	M	18.18	13,259	241,049	0
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Option Exercise	M	8.28	7,500	62,100	0
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Option Exercise	M	7.51	7,500	56,325	0
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Option Exercise	M	18.30	7,500	137,250	0
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Buy	M	21.14	12,039	254,504	163,431	151.4 K to 163.4 K (+7.95 %)
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Buy	M	18.18	13,259	241,049	151,392	138.1 K to 151.4 K (+9.60 %)
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Buy	M	8.28	7,500	62,100	138,133	130.6 K to 138.1 K (+5.74 %)
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Buy	M	7.51	7,500	56,325	130,633	123.1 K to 130.6 K (+6.09 %)
Nov 13 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Buy	M	18.30	7,500	137,250	123,133	115.6 K to 123.1 K (+6.49 %)
Sep 05 2017	MDCO	MEDICINES CO /DE	MEANWELL CLIVE	CEO	Grant	A	31.18	237	7,390	386,732	386.5 K to 386.7 K (+0.06 %)
Sep 05 2017	MDCO	MEDICINES CO /DE	O'Connor William Bernard	Chief Financial Off ...	Grant	A	31.18	237	7,390	24,215	24 K to 24.2 K (+0.99 %)
Sep 05 2017	MDCO	MEDICINES CO /DE	Rodin Stephen M	EVP and General Cou ...	Grant	A	31.18	237	7,390	23,931	23.7 K to 23.9 K (+1.00 %)
Sep 05 2017	MDCO	MEDICINES CO /DE	Cox Christopher T	EVP & Chief Corp. D ...	Grant	A	31.18	237	7,390	45,613	45.4 K to 45.6 K (+0.52 %)
Sep 05 2017	MDCO	MEDICINES CO /DE	Frazier Jeff	EVP, Chief Human St ...	Grant	A	31.18	237	7,390	35,446	35.2 K to 35.4 K (+0.67 %)
Aug 31 2017	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Grant	A	36.69	7,146	262,187	1,752,000	1.7 M to 1.8 M (+0.41 %)
Jun 07 2017	MDCO	MEDICINES CO /DE	Frazier Jeff	EVP, Chief Human St ...	Payment of Exercise	F	40.00	2,168	86,720	35,209	37.4 K to 35.2 K (-5.80 %)
May 30 2017	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Option Exercise	A	39.39	8,577	337,848	8,577
May 30 2017	MDCO	MEDICINES CO /DE	DENNER ALEXANDER J	Director	Grant	A	0.00	3,237	0	6,663	3.4 K to 6.7 K (+94.48 %)
May 30 2017	MDCO	MEDICINES CO /DE	Kelly John C.	Director	Option Exercise	A	39.39	8,577	337,848	8,577
May 30 2017	MDCO	MEDICINES CO /DE	Kelly John C.	Director	Grant	A	0.00	3,237	0	24,719	21.5 K to 24.7 K (+15.07 %)
May 30 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Option Exercise	A	39.39	8,577	337,848	8,577
May 30 2017	MDCO	MEDICINES CO /DE	HUGIN ROBERT J	Director	Grant	A	0.00	3,237	0	115,633	112.4 K to 115.6 K (+2.88 %)
May 30 2017	MDCO	MEDICINES CO /DE	WYATT ELIZABETH H S	Director	Option Exercise	A	39.39	8,577	337,848	8,577
May 30 2017	MDCO	MEDICINES CO /DE	WYATT ELIZABETH H S	Director	Grant	A	0.00	3,237	0	53,133	49.9 K to 53.1 K (+6.49 %)
May 30 2017	MDCO	MEDICINES CO /DE	ESHELMAN FREDRIC N	Director	Option Exercise	A	39.39	13,577	534,798	13,577
May 30 2017	MDCO	MEDICINES CO /DE	ESHELMAN FREDRIC N	Director	Grant	A	0.00	3,237	0	928,383	925.1 K to 928.4 K (+0.35 %)
May 30 2017	MDCO	MEDICINES CO /DE	CROUSE WILLIAM	Director	Option Exercise	A	39.39	8,577	337,848	8,577
May 30 2017	MDCO	MEDICINES CO /DE	CROUSE WILLIAM	Director	Grant	A	0.00	3,237	0	53,133	49.9 K to 53.1 K (+6.49 %)
May 30 2017	MDCO	MEDICINES CO /DE	KESSLER ARMIN M	Director	Option Exercise	A	39.39	8,577	337,848	8,577
May 30 2017	MDCO	MEDICINES CO /DE	KESSLER ARMIN M	Director	Grant	A	0.00	3,237	0	150,993	147.8 K to 151 K (+2.19 %)
May 30 2017	MDCO	MEDICINES CO /DE	Panayiotopoulos Paris	Director	Option Exercise	A	39.39	8,577	337,848	8,577

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