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General | Insiders | Insider Transactions | Monthly Overview | Weekly Overview

Overview of all insider trading transactions in SIRNA THERAPEUTICS INC. Get notifications about new insider transactions in SIRNA THERAPEUTICS INC for free.

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Date	Ticker	Company	Owner	Relationship	Transaction	Code	Cost ($)	Shares	Transaction Value ($)	Total Shares	% Holdings
Sep 09 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Buy	J	0.00	182	0	196	14 to 196 (+1,300.00 %)
Sep 09 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Buy	J	0.00	14	0	14	0 to 14
Sep 09 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES III LP	10% Owner	Sell	J	0.00	1,999,984	0	4,038,821	6 M to 4 M (-33.12 %)
Sep 09 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES	10% Owner	Sell	J	0.00	449,948	0	908,783	1.4 M to 908.8 K (-33.12 %)
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK MANAGEMENT III LLC	10% Owner	Option Exercise	P	2.00	950,093	1,900,186	950,093
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK MANAGEMENT III LLC	10% Owner	Option Exercise	J	3.85	950,093	3,657,858	0
Aug 31 2005	RNAI	SIRNA THERAPEUTICS ...	LANGER DENNIS	Director	Option Exercise	A	3.67	16,348	59,997	16,348
Aug 31 2005	RNAI	SIRNA THERAPEUTICS ...	LANGER DENNIS	Director	Option Exercise	A	3.67	30,000	110,100	30,000
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VEF MANAGEMENT III LLC	10% Owner	Option Exercise	P	2.00	23,752	47,504	23,752
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VEF MANAGEMENT III LLC	10% Owner	Option Exercise	J	3.85	23,752	91,445	0
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES III LP	10% Owner	Option Exercise	P	2.00	950,093	1,900,186	950,093
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES III LP	10% Owner	Option Exercise	J	3.85	950,093	3,657,858	0
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	P	2.00	23,752	47,504	23,752
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	3.85	23,752	91,445	0
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	P	2.00	950,093	1,900,186	950,093
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	3.85	950,093	3,657,858	0
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	P	2.00	213,771	427,542	213,771
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	3.85	213,771	823,018	0
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ENTREPRENEURS FUND III ...	10% Owner	Option Exercise	P	2.00	23,752	47,504	23,752
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ENTREPRENEURS FUND III ...	10% Owner	Option Exercise	J	3.85	23,752	91,445	0
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES	10% Owner	Option Exercise	P	2.00	213,771	427,542	213,771
Jul 14 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES	10% Owner	Option Exercise	J	3.85	213,771	823,018	0
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK MANAGEMENT III LLC	10% Owner	Option Exercise	P	1.92	360,000	691,200	360,000
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK MANAGEMENT III LLC	10% Owner	Buy	P	1.60	1,000,000	1,600,000	6,038,805	5 M to 6 M (+19.85 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VEF MANAGEMENT III LLC	10% Owner	Option Exercise	P	1.92	8,999	17,278	8,999
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VEF MANAGEMENT III LLC	10% Owner	Buy	P	1.60	24,999	39,998	150,969	126 K to 151 K (+19.85 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	P	1.92	8,999	17,278	8,999
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	P	1.92	360,000	691,200	360,000
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	P	1.92	81,000	155,520	81,000
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Buy	P	1.60	24,999	39,998	150,969	126 K to 151 K (+19.85 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Buy	P	1.60	1,000,000	1,600,000	6,038,805	5 M to 6 M (+19.85 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Buy	P	1.60	225,000	360,000	1,358,731	1.1 M to 1.4 M (+19.85 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE/	10% Owner	Option Exercise	P	1.92	48,136	92,421	152,763
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE/	10% Owner	Option Exercise	P	1.92	1,042,346	2,001,304	3,308,010
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE/	10% Owner	Option Exercise	P	1.92	4,107	7,885	13,034
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE/	10% Owner	Option Exercise	P	1.92	2,284	4,385	7,249
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE/	10% Owner	Buy	P	1.60	133,712	213,939	652,658	518.9 K to 652.7 K (+25.77 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE/	10% Owner	Buy	P	1.60	2,895,406	4,632,650	14,132,739	11.2 M to 14.1 M (+25.77 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE/	10% Owner	Buy	P	1.60	11,411	18,258	55,697	44.3 K to 55.7 K (+25.77 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE/	10% Owner	Buy	P	1.60	6,346	10,154	30,976	24.6 K to 31 K (+25.77 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	P	1.92	48,136	92,421	152,763
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	P	1.92	1,042,346	2,001,304	3,308,010
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	P	1.92	4,107	7,885	13,034
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	P	1.92	2,284	4,385	7,249
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	P	1.92	28,125	54,000	89,257
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Buy	P	1.60	133,712	213,939	652,658	518.9 K to 652.7 K (+25.77 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Buy	P	1.60	2,895,406	4,632,650	14,132,739	11.2 M to 14.1 M (+25.77 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Buy	P	1.60	11,411	18,258	55,697	44.3 K to 55.7 K (+25.77 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Buy	P	1.60	6,346	10,154	30,976	24.6 K to 31 K (+25.77 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Buy	P	1.60	78,126	125,002	381,336	303.2 K to 381.3 K (+25.77 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ENTREPRENEURS FUND III ...	10% Owner	Option Exercise	P	1.92	8,999	17,278	8,999
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ENTREPRENEURS FUND III ...	10% Owner	Buy	P	1.60	24,999	39,998	150,969	126 K to 151 K (+19.85 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	P	1.92	4,470	8,582	4,470
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	P	1.92	445,529	855,416	445,529
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Buy	P	1.60	12,418	19,869	58,267	45.8 K to 58.3 K (+27.08 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Buy	P	1.60	1,237,582	1,980,131	5,807,127	4.6 M to 5.8 M (+27.08 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES III LP	10% Owner	Option Exercise	P	1.92	360,000	691,200	360,000
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES III LP	10% Owner	Buy	P	1.60	1,000,000	1,600,000	6,038,805	5 M to 6 M (+19.85 %)
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES	10% Owner	Option Exercise	P	1.92	81,000	155,520	81,000
Jul 08 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK ASSOCIATES	10% Owner	Buy	P	1.60	225,000	360,000	1,358,731	1.1 M to 1.4 M (+19.85 %)
Jul 07 2005	RNAI	SIRNA THERAPEUTICS ...	FRENCH J MICHAEL	Sr. VP, Corporate D ...	Option Exercise	A	1.62	71,066	115,127	71,066
Jul 07 2005	RNAI	SIRNA THERAPEUTICS ...	FRENCH J MICHAEL	Sr. VP, Corporate D ...	Option Exercise	A	1.62	228,934	370,873	228,934
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	CHOWRIRA BHARAT M	VP Legal & Chief Pa ...	Option Exercise	A	3.07	18,333	56,282	18,333
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	CHOWRIRA BHARAT M	VP Legal & Chief Pa ...	Option Exercise	A	3.07	21,667	66,518	21,667
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	GUERCIOLINI ROBERTO	Chief Med Off & Sr. ...	Option Exercise	A	3.07	26,833	82,377	26,833
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	GUERCIOLINI ROBERTO	Chief Med Off & Sr. ...	Option Exercise	A	3.07	1,167	3,583	1,167
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	POLISKY BARRY	Sr. Vice President, ...	Option Exercise	A	3.07	18,332	56,279	18,332
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	POLISKY BARRY	Sr. Vice President, ...	Option Exercise	A	3.07	21,668	66,521	21,668
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	ROBIN HOWARD W	President & CEO	Option Exercise	A	3.07	47,916	147,102	47,916
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	ROBIN HOWARD W	President & CEO	Option Exercise	A	3.07	2,084	6,398	2,084
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	SCHMIEG MARTIN E	Sr. Vice President ...	Option Exercise	A	3.07	57,500	176,525	57,500
Feb 07 2005	RNAI	SIRNA THERAPEUTICS ...	SCHMIEG MARTIN E	Sr. Vice President ...	Option Exercise	A	3.07	2,500	7,675	2,500
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Option Exercise	X	2.52	810,315	2,041,994	891,346
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Option Exercise	P	3.85	891,346	3,431,682	1,701,661
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Option Exercise	P	2.52	810,315	2,041,994	810,315
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Option Exercise	H	2.52	810,315	2,041,994	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Option Exercise	X	2.52	8,130	20,488	8,943
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Option Exercise	P	3.85	8,943	34,431	17,073
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Option Exercise	P	2.52	8,130	20,488	8,130
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Option Exercise	H	2.52	8,130	20,488	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Buy	X	2.52	810,315	2,041,994	4,569,545	3.8 M to 4.6 M (+21.56 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	MRNA FUND II LP	10% Owner	Buy	X	2.52	8,130	20,488	45,849	37.7 K to 45.8 K (+21.55 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	X	2.52	8,130	20,488	8,943
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	P	3.85	8,943	34,431	17,073
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	P	2.52	8,130	20,488	8,130
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	H	2.52	8,130	20,488	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	X	2.52	810,315	2,041,994	891,346
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	P	3.85	891,346	3,431,682	1,701,661
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	P	2.52	810,315	2,041,994	810,315
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Option Exercise	H	2.52	810,315	2,041,994	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Buy	X	2.52	8,130	20,488	45,849	37.7 K to 45.8 K (+21.55 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	OXFORD BIOSCIENCE PARTNERS IV ...	10% Owner	Buy	X	2.52	810,315	2,041,994	4,569,545	3.8 M to 4.6 M (+21.56 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK MANAGEMENT III LLC	10% Owner	Option Exercise	X	2.52	863,721	2,176,577	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK MANAGEMENT III LLC	10% Owner	Option Exercise	J	2.52	863,721	2,176,577	863,721
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK MANAGEMENT III LLC	10% Owner	Option Exercise	J	3.85	950,093	3,657,858	950,093
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK MANAGEMENT III LLC	10% Owner	Option Exercise	J	2.52	863,721	2,176,577	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VENROCK MANAGEMENT III LLC	10% Owner	Buy	X	2.52	863,721	2,176,577	5,038,805	4.2 M to 5 M (+20.69 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VEF MANAGEMENT III LLC	10% Owner	Option Exercise	X	2.52	21,593	54,414	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VEF MANAGEMENT III LLC	10% Owner	Option Exercise	J	2.52	21,593	54,414	21,593
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VEF MANAGEMENT III LLC	10% Owner	Option Exercise	J	3.85	23,752	91,445	23,752
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VEF MANAGEMENT III LLC	10% Owner	Option Exercise	J	2.52	21,593	54,414	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	VEF MANAGEMENT III LLC	10% Owner	Buy	X	2.52	21,593	54,414	125,970	104.4 K to 126 K (+20.69 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	X	2.52	21,593	54,414	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	2.52	21,593	54,414	21,593
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	3.85	23,752	91,445	23,752
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	2.52	21,593	54,414	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	X	2.52	863,721	2,176,577	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	2.52	863,721	2,176,577	863,721
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	3.85	950,093	3,657,858	950,093
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	2.52	863,721	2,176,577	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	X	2.52	194,337	489,729	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	2.52	194,337	489,729	194,337
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	3.85	213,771	823,018	213,771
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Option Exercise	J	2.52	194,337	489,729	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Buy	X	2.52	21,593	54,414	125,970	104.4 K to 126 K (+20.69 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Buy	X	2.52	863,721	2,176,577	5,038,805	4.2 M to 5 M (+20.69 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	ROBERTS BRYAN E	Director	Buy	X	2.52	194,337	489,729	1,133,731	939.4 K to 1.1 M (+20.69 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	X	2.52	14,910	37,573	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	X	2.52	1,211	3,052	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	X	2.52	552,601	1,392,555	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	X	2.52	2,177	5,486	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	X	2.52	25,519	64,308	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	3.85	16,401	63,144	16,401
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	3.85	1,332	5,128	1,332
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	3.85	607,861	2,340,265	607,861
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	3.85	2,394	9,217	2,394
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	3.85	28,070	108,070	28,070
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	2.52	14,910	37,573	14,910
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	2.52	1,211	3,052	1,211
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	2.52	552,601	1,392,555	552,601
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	2.52	2,177	5,486	2,177
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	P	2.52	25,519	64,308	25,519
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	H	2.52	14,910	37,573	44,731
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	H	2.52	1,211	3,052	76,557
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	H	2.52	552,601	1,392,555	1,657,803
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	H	2.52	2,177	5,486	6,533
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Option Exercise	H	2.52	25,519	64,308	76,557
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Buy	X	2.52	1,211	3,052	24,630	23.4 K to 24.6 K (+5.17 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Buy	X	2.52	552,601	1,392,555	11,237,333	10.7 M to 11.2 M (+5.17 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Buy	X	2.52	2,177	5,486	44,286	42.1 K to 44.3 K (+5.17 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Buy	X	2.52	14,910	37,573	288,300	273.4 K to 288.3 K (+5.45 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	CREDIT SUISSE FIRST BOSTON/	10% Owner	Buy	X	2.52	25,519	64,308	518,946	493.4 K to 518.9 K (+5.17 %)
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	X	2.52	14,910	37,573	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	X	2.52	1,211	3,052	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	X	2.52	552,601	1,392,555	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	X	2.52	2,177	5,486	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	X	2.52	25,519	64,308	0
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	P	3.85	16,401	63,144	16,401
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	P	3.85	1,332	5,128	1,332
Jan 04 2005	RNAI	SIRNA THERAPEUTICS ...	NIEDEL JAMES	Director	Option Exercise	P	3.85	607,861	2,340,265	607,861

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