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General | Insiders | Insider Transactions | Monthly Overview | Weekly Overview

Overview of all insider trading transactions in ALNYLAM PHARMACEUTICALS, INC.. Get notifications about new insider transactions in ALNYLAM PHARMACEUTICALS, INC. for free.

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Date	Ticker	Company	Owner	Relationship	Transaction	Code	Cost ($)	Shares	Transaction Value ($)	Total Shares	% Holdings
Dec 02 2011	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	A	7.10	100,000	710,000	100,000
Dec 02 2011	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	A	7.10	150,000	1,065,000	150,000
Nov 16 2011	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	P	7.09	704	4,994	1,446	742 to 1.4 K (+94.88 %)
Nov 16 2011	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	P	7.08	1,411	9,997	50,391	49 K to 50.4 K (+2.88 %)
Oct 13 2011	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	P	6.73	742	4,996	742	0 to 742
Oct 13 2011	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	P	6.75	1,480	9,989	48,980	47.5 K to 49 K (+3.12 %)
Oct 13 2011	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Gift	G	0.00	2,500	0	47,500	50 K to 47.5 K (-5.00 %)
Jun 13 2011	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Chief Medical ...	Option Exercise	A	9.30	100,000	930,000	100,000
Jun 13 2011	ALNY	ALNYLAM PHARMACEUT ...	PAUL STEVEN M	Director	Option Exercise	A	9.30	15,000	139,500	15,000
Jun 13 2011	ALNY	ALNYLAM PHARMACEUT ...	Fanucci Marsha	Director	Option Exercise	A	9.30	15,000	139,500	15,000
Jun 13 2011	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	A	9.30	25,000	232,500	25,000
Jun 13 2011	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	9.30	30,000	279,000	30,000
Jun 13 2011	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Option Exercise	A	9.30	15,000	139,500	15,000
Jun 13 2011	ALNY	ALNYLAM PHARMACEUT ...	DZAU VICTOR J	Director	Option Exercise	A	9.30	15,000	139,500	15,000
Jun 13 2011	ALNY	ALNYLAM PHARMACEUT ...	CLARKE JOHN K	Director	Option Exercise	A	9.30	15,000	139,500	15,000
Mar 03 2011	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	A	10.98	25,000	274,500	25,000
Dec 10 2010	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP, Chief Business ...	Option Exercise	A	9.14	27,589	252,163	27,589
Dec 10 2010	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Clinical Resea ...	Option Exercise	A	9.14	30,000	274,200	30,000
Dec 10 2010	ALNY	ALNYLAM PHARMACEUT ...	Allen Patricia L	VP of Finance and T ...	Option Exercise	A	9.14	25,000	228,500	25,000
Dec 10 2010	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	A	9.14	100,000	914,000	100,000
Dec 10 2010	ALNY	ALNYLAM PHARMACEUT ...	KOBLAN KENNETH S	Chief Scientific Of ...	Option Exercise	A	9.14	10,000	91,400	10,000
Dec 10 2010	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	A	9.14	150,000	1,371,000	150,000
Dec 10 2010	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	9.14	15,000	137,100	15,000
Dec 10 2010	ALNY	ALNYLAM PHARMACEUT ...	Fanucci Marsha	Director	Option Exercise	A	9.14	30,000	274,200	30,000
Sep 24 2010	ALNY	ALNYLAM PHARMACEUT ...	PAUL STEVEN M	Director	Option Exercise	A	14.67	30,000	440,100	30,000
Aug 18 2010	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	50,000	23,750	14,102
Aug 18 2010	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	50,000	23,750	50,000	0 to 50 K
Jun 18 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Option Exercise	M	7.02	12,100	84,942	0
Jun 18 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Sell	S	15.19	12,100	183,826	0	12.1 K to 0 (-100.00 %)
Jun 18 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Buy	M	7.02	12,100	84,942	12,100	0 to 12.1 K
Jun 18 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Sell	S	15.16	8,667	131,392	0	8.7 K to 0 (-100.00 %)
Jun 18 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Sell	S	15.70	1,333	20,930	8,667	10 K to 8.7 K (-13.33 %)
Jun 17 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Option Exercise	M	7.02	30,000	210,600	12,100
Jun 17 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Sell	S	16.00	30,000	480,090	10,000	40 K to 10 K (-75.00 %)
Jun 17 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Buy	M	7.02	30,000	210,600	40,000	10 K to 40 K (+300.00 %)
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Option Exercise	M	7.02	2,900	20,358	42,100
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Option Exercise	M	7.02	5,000	35,100	45,000
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Option Exercise	M	7.02	10,000	70,200	50,000
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Option Exercise	M	7.02	15,000	105,300	60,000
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Sell	S	16.05	2,900	46,548	10,000	12.9 K to 10 K (-22.48 %)
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Buy	M	7.02	2,900	20,358	12,900	10 K to 12.9 K (+29.00 %)
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Sell	S	16.10	5,000	80,482	10,000	15 K to 10 K (-33.33 %)
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Buy	M	7.02	5,000	35,100	15,000	10 K to 15 K (+50.00 %)
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Sell	S	16.10	10,000	160,963	10,000	20 K to 10 K (-50.00 %)
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Buy	M	7.02	10,000	70,200	20,000	10 K to 20 K (+100.00 %)
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Sell	S	15.95	15,000	239,250	10,000	25 K to 10 K (-60.00 %)
Jun 15 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Buy	M	7.02	15,000	105,300	25,000	10 K to 25 K (+150.00 %)
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Option Exercise	A	15.82	15,000	237,300	15,000
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	A	15.82	25,000	395,500	25,000
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Option Exercise	A	15.82	15,000	237,300	15,000
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	SATO VICKI L	Director	Option Exercise	A	15.82	15,000	237,300	15,000
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	DZAU VICTOR J	Director	Option Exercise	A	15.82	15,000	237,300	15,000
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	CLARKE JOHN K	Director	Option Exercise	A	15.82	15,000	237,300	15,000
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	15.82	15,000	237,300	15,000
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	J	0.00	105,400	0	105,400	0 to 105.4 K
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	J	0.00	105,400	0	0	105.4 K to 0 (-100.00 %)
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	J	0.00	29,600	0	105,400	75.8 K to 105.4 K (+39.05 %)
Jun 04 2010	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	J	0.00	29,600	0	147,230	176.8 K to 147.2 K (-16.74 %)
Jun 03 2010	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP, Chief Business ...	Option Exercise	A	15.40	175,000	2,695,000	175,000
Apr 26 2010	ALNY	ALNYLAM PHARMACEUT ...	NOVARTIS AG	10% Owner	Buy	P	17.99	55,223	993,462	5,602,898	5.5 M to 5.6 M (+1.00 %)
Dec 11 2009	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	16.43	15,000	246,450	15,000
Dec 11 2009	ALNY	ALNYLAM PHARMACEUT ...	Allen Patricia L	VP of Finance/Treas ...	Option Exercise	A	16.43	25,000	410,750	25,000
Dec 11 2009	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Clinical Resea ...	Option Exercise	A	16.43	45,000	739,350	45,000
Dec 11 2009	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	A	16.43	65,000	1,067,950	65,000
Dec 11 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	A	16.43	105,000	1,725,150	105,000
Sep 11 2009	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	22.26	15,600	347,289	159,088	174.7 K to 159.1 K (-8.93 %)
Sep 11 2009	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	22.10	30,000	662,931	174,688	204.7 K to 174.7 K (-14.66 %)
Sep 09 2009	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	22.02	29,400	647,482	204,688	234.1 K to 204.7 K (-12.56 %)
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	28,200	13,395	64,102
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	11,800	5,605	0
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	40,000	19,000	11,800
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	400	190	51,800
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	39,600	18,810	52,200
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	21.37	28,200	602,527	0	28.2 K to 0 (-100.00 %)
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	28,200	13,395	28,200	0 to 28.2 K
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	21.37	11,800	252,121	0	11.8 K to 0 (-100.00 %)
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	11,800	5,605	11,800	0 to 11.8 K
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	21.40	40,000	855,840	0	40 K to 0 (-100.00 %)
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	40,000	19,000	40,000	0 to 40 K
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	22.16	400	8,863	0	400 to 0 (-100.00 %)
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	400	190	400	0 to 400
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	21.43	39,600	848,727	0	39.6 K to 0 (-100.00 %)
Jun 18 2009	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	39,600	18,810	39,600	0 to 39.6 K
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Option Exercise	A	22.09	15,000	331,350	15,000
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	A	22.09	25,000	552,250	25,000
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	22.09	15,000	331,350	15,000
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	J	0.00	176,830	0	176,830	0 to 176.8 K
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	J	0.00	176,830	0	0	176.8 K to 0 (-100.00 %)
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Sell	J	0.00	176,830	0	75,800	252.6 K to 75.8 K (-70.00 %)
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	J	0.00	176,830	0	252,630	75.8 K to 252.6 K (+233.28 %)
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	SCOLNICK EDWARD M	Director	Option Exercise	A	22.09	15,000	331,350	15,000
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Option Exercise	A	22.09	15,000	331,350	15,000
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	SATO VICKI L	Director	Option Exercise	A	22.09	15,000	331,350	15,000
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	DZAU VICTOR J	Director	Option Exercise	A	22.09	15,000	331,350	15,000
Jun 12 2009	ALNY	ALNYLAM PHARMACEUT ...	CLARKE JOHN K	Director	Option Exercise	A	22.09	15,000	331,350	15,000
May 06 2009	ALNY	ALNYLAM PHARMACEUT ...	NOVARTIS AG	10% Owner	Buy	P	17.50	65,922	1,153,635	5,547,675	5.5 M to 5.5 M (+1.20 %)
Apr 24 2009	ALNY	ALNYLAM PHARMACEUT ...	Allen Patricia L	VP of Finance/Treas ...	Option Exercise	M	0.95	25,000	23,750	33,947
Apr 24 2009	ALNY	ALNYLAM PHARMACEUT ...	Allen Patricia L	VP of Finance/Treas ...	Sell	S	17.63	25,000	440,745	0	25 K to 0 (-100.00 %)
Apr 24 2009	ALNY	ALNYLAM PHARMACEUT ...	Allen Patricia L	VP of Finance/Treas ...	Buy	M	0.95	25,000	23,750	25,000	0 to 25 K
Dec 11 2008	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	21.35	15,000	320,250	15,000
Dec 11 2008	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Gift	G	0.00	176,830	0	176,830	0 to 176.8 K
Dec 11 2008	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Gift	G	0.00	176,830	0	75,800	252.6 K to 75.8 K (-70.00 %)
Dec 11 2008	ALNY	ALNYLAM PHARMACEUT ...	Schmidt John A Jr	SVP, Chief Scientif ...	Option Exercise	A	21.35	15,000	320,250	15,000
Dec 11 2008	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	A	21.35	90,000	1,921,500	90,000
Dec 11 2008	ALNY	ALNYLAM PHARMACEUT ...	Allen Patricia L	VP of Finance/Treas ...	Option Exercise	A	21.35	31,663	676,005	31,663
Dec 11 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	A	21.35	153,320	3,273,382	153,320
Oct 01 2008	ALNY	ALNYLAM PHARMACEUT ...	Schmidt John A Jr	SVP, Chief Scientif ...	Option Exercise	A	30.25	200,000	6,050,000	200,000
Aug 19 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	750	356	92,302
Aug 19 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Gift	G	0.00	750	0	0	750 to 0 (-100.00 %)
Aug 19 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	750	356	750	0 to 750
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	37,500	17,813	93,052
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	37,500	17,813	130,552
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	34.23	37,500	1,283,513	0	37.5 K to 0 (-100.00 %)
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	37,500	17,813	37,500	0 to 37.5 K
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Sell	S	33.95	37,500	1,273,005	0	37.5 K to 0 (-100.00 %)
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	37,500	17,813	37,500	0 to 37.5 K
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	M	0.95	30,889	29,345	48,058
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Sell	S	33.94	30,889	1,048,379	0	30.9 K to 0 (-100.00 %)
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	M	0.95	30,889	29,345	30,889	0 to 30.9 K
Aug 15 2008	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Sell	S	33.92	4,551	154,347	0	4.6 K to 0 (-100.00 %)
Jul 02 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	3,000	1,425	168,052
Jul 02 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Gift	G	0.00	1,500	0	0	1.5 K to 0 (-100.00 %)
Jul 02 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Gift	G	0.00	1,500	0	1,500	3 K to 1.5 K (-50.00 %)
Jul 02 2008	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	3,000	1,425	3,000	0 to 3 K
Jun 05 2008	ALNY	ALNYLAM PHARMACEUT ...	VINCENT JAMES L	Director	Option Exercise	A	27.28	15,000	409,200	15,000
Jun 05 2008	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	A	27.28	25,000	682,000	25,000
Jun 05 2008	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	27.28	15,000	409,200	15,000
Jun 05 2008	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Option Exercise	A	27.28	15,000	409,200	15,000
Jun 05 2008	ALNY	ALNYLAM PHARMACEUT ...	SATO VICKI L	Director	Option Exercise	A	27.28	15,000	409,200	15,000
Jun 05 2008	ALNY	ALNYLAM PHARMACEUT ...	DZAU VICTOR J	Director	Option Exercise	A	27.28	15,000	409,200	15,000
Jun 05 2008	ALNY	ALNYLAM PHARMACEUT ...	CLARKE JOHN K	Director	Option Exercise	A	27.28	15,000	409,200	15,000
May 14 2008	ALNY	ALNYLAM PHARMACEUT ...	NOVARTIS AG	10% Owner	Buy	P	25.29	213,888	5,409,228	5,481,753	5.3 M to 5.5 M (+4.06 %)
Feb 13 2008	ALNY	ALNYLAM PHARMACEUT ...	SCOLNICK EDWARD M	Director	Option Exercise	A	32.97	45,000	1,483,650	45,000
Dec 14 2007	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	31.39	15,000	470,850	15,000
Dec 14 2007	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	31.29	25,000	782,250	25,000
Dec 14 2007	ALNY	ALNYLAM PHARMACEUT ...	Allen Patricia L	VP of Finance/Treas ...	Option Exercise	A	31.39	32,625	1,024,099	32,625
Dec 14 2007	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	A	31.39	150,600	4,727,334	150,600
Dec 14 2007	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	A	31.39	80,000	2,511,200	80,000
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	31.92	200	6,384	62,385	62.6 K to 62.4 K (-0.32 %)
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	31.90	5,692	181,575	62,585	68.3 K to 62.6 K (-8.34 %)
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	31.85	1,300	41,405	68,277	69.6 K to 68.3 K (-1.87 %)
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Gift	G	0.00	4,000	0	234,088	238.1 K to 234.1 K (-1.68 %)
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Option Exercise	M	14.74	10,000	147,400	0
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Option Exercise	M	7.08	10,000	70,800	0
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	33.01	1,400	46,214	69,577	71 K to 69.6 K (-1.97 %)
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	33.00	1,800	59,400	70,977	72.8 K to 71 K (-2.47 %)
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	32.50	5,836	189,670	72,777	78.6 K to 72.8 K (-7.42 %)
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	32.35	400	12,940	78,613	79 K to 78.6 K (-0.51 %)
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	32.30	2,150	69,445	79,013	81.2 K to 79 K (-2.65 %)
Dec 04 2007	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Sell	S	33.35	657	21,911	81,163	81.8 K to 81.2 K (-0.80 %)

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