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General | Insiders | Insider Transactions | Monthly Overview | Weekly Overview

Overview of all insider trading transactions in ALNYLAM PHARMACEUTICALS, INC.. Get notifications about new insider transactions in ALNYLAM PHARMACEUTICALS, INC. for free.

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Date	Ticker	Company	Owner	Relationship	Transaction	Code	Cost ($)	Shares	Transaction Value ($)	Total Shares	% Holdings
Sep 12 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	58.18	700	40,724	12,588	13.3 K to 12.6 K (-5.27 %)
Sep 12 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	57.39	5,550	318,515	13,288	18.8 K to 13.3 K (-29.46 %)
Sep 12 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	9.30	6,250	58,125	18,838	12.6 K to 18.8 K (+49.65 %)
Aug 16 2013	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	0.95	60,000	57,000	45,263
Aug 16 2013	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	49.06	40,237	1,974,188	18,617	58.9 K to 18.6 K (-68.37 %)
Aug 16 2013	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	48.77	19,763	963,938	58,854	78.6 K to 58.9 K (-25.14 %)
Aug 16 2013	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	0.95	60,000	57,000	78,617	18.6 K to 78.6 K (+322.29 %)
Jul 12 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance & Treas ...	Option Exercise	M	31.39	14,200	445,738	0
Jul 12 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance & Treas ...	Sell	S	50.00	14,200	710,000	7,847	22 K to 7.8 K (-64.41 %)
Jul 12 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance & Treas ...	Buy	M	31.39	14,200	445,738	22,047	7.8 K to 22 K (+180.96 %)
Jul 12 2013	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Option Exercise	M	0.95	60,000	57,000	13,684
Jul 12 2013	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	37.11	60,000	2,226,822	18,617	78.6 K to 18.6 K (-76.32 %)
Jul 12 2013	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Buy	M	0.95	60,000	57,000	78,617	18.6 K to 78.6 K (+322.29 %)
Jul 02 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	M	22.75	15,000	341,250	0
Jul 02 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	M	21.35	12,000	256,200	0
Jul 02 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Sell	S	32.00	15,000	480,000	7,847	22.8 K to 7.8 K (-65.65 %)
Jul 02 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Buy	M	22.75	15,000	341,250	22,847	7.8 K to 22.8 K (+191.16 %)
Jul 02 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Sell	S	32.00	12,000	384,000	7,847	19.8 K to 7.8 K (-60.46 %)
Jul 02 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Buy	M	21.35	12,000	256,200	19,847	7.8 K to 19.8 K (+152.92 %)
Jun 10 2013	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Option Exercise	A	30.09	15,000	451,350	15,000
Jun 19 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	M	16.43	13,000	213,590	3,000
Jun 19 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	M	10.98	6,250	68,625	12,500
Jun 19 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	M	9.14	4,375	39,988	6,563
Jun 19 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Sell	S	29.93	6,250	187,079	7,847	14.1 K to 7.8 K (-44.34 %)
Jun 19 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Buy	M	10.98	6,250	68,625	14,097	7.8 K to 14.1 K (+79.65 %)
Jun 19 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Sell	S	29.93	4,375	130,956	7,847	12.2 K to 7.8 K (-35.80 %)
Jun 19 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Buy	M	9.14	4,375	39,988	12,222	7.8 K to 12.2 K (+55.75 %)
Jun 19 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Sell	S	29.93	13,000	389,125	7,847	20.8 K to 7.8 K (-62.36 %)
Jun 19 2013	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Buy	M	16.43	13,000	213,590	20,847	7.8 K to 20.8 K (+165.67 %)
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	9.30	6,250	58,125	50,000
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	9.14	3,750	34,275	11,250
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	7.10	5,000	35,500	25,000
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	31.75	100	3,175	12,588	12.7 K to 12.6 K (-0.79 %)
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	31.07	4,900	152,249	12,688	17.6 K to 12.7 K (-27.86 %)
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	7.10	5,000	35,500	17,588	12.6 K to 17.6 K (+39.72 %)
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	31.07	6,250	194,196	12,588	18.8 K to 12.6 K (-33.18 %)
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	9.30	6,250	58,125	18,838	12.6 K to 18.8 K (+49.65 %)
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	31.07	3,750	116,517	12,588	16.3 K to 12.6 K (-22.95 %)
Jun 13 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	9.14	3,750	34,275	16,338	12.6 K to 16.3 K (+29.79 %)
Jun 10 2013	ALNY	ALNYLAM PHARMACEUT ...	PAUL STEVEN M	Director	Option Exercise	A	30.09	15,000	451,350	15,000
Jun 10 2013	ALNY	ALNYLAM PHARMACEUT ...	DZAU VICTOR J	Director	Option Exercise	A	30.09	15,000	451,350	15,000
Jun 10 2013	ALNY	ALNYLAM PHARMACEUT ...	CLARKE JOHN K	Director	Option Exercise	A	30.09	15,000	451,350	15,000
Jun 10 2013	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	A	30.09	25,000	752,250	25,000
Jun 10 2013	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	30.09	30,000	902,700	30,000
Jun 10 2013	ALNY	ALNYLAM PHARMACEUT ...	Fanucci Marsha	Director	Option Exercise	A	30.09	15,000	451,350	15,000
Jun 10 2013	ALNY	ALNYLAM PHARMACEUT ...	Ausiello Dennis A	Director	Option Exercise	A	30.09	15,000	451,350	15,000
Jun 10 2013	ALNY	ALNYLAM PHARMACEUT ...	Ausiello Dennis A	Director	Option Exercise	A	30.09	30,000	902,700	30,000
May 30 2013	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP and Chief Busin ...	Option Exercise	M	7.10	5,000	35,500	30,000
May 30 2013	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP and Chief Busin ...	Sell	S	30.00	5,000	150,000	11,681	16.7 K to 11.7 K (-29.97 %)
May 30 2013	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP and Chief Busin ...	Buy	M	7.10	5,000	35,500	16,681	11.7 K to 16.7 K (+42.80 %)
May 30 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	M	0.95	14,928	14,182	0
May 30 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	M	0.95	7,894	7,499	0
May 30 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Sell	S	30.00	14,928	447,840	4,572	19.5 K to 4.6 K (-76.55 %)
May 30 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	M	0.95	14,928	14,182	19,500	4.6 K to 19.5 K (+326.51 %)
May 30 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Sell	S	30.00	7,894	236,820	4,572	12.5 K to 4.6 K (-63.32 %)
May 30 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	M	0.95	7,894	7,499	12,466	4.6 K to 12.5 K (+172.66 %)
Mar 26 2013	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	M	0.95	26,000	24,700	0
Mar 26 2013	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	M	0.95	26,631	25,299	26,000
Mar 26 2013	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Sell	S	23.41	26,000	608,577	0	26 K to 0 (-100.00 %)
Mar 26 2013	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Buy	M	0.95	26,000	24,700	26,000	0 to 26 K
Mar 26 2013	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Sell	S	23.56	26,631	627,557	0	26.6 K to 0 (-100.00 %)
Mar 26 2013	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Buy	M	0.95	26,631	25,299	26,631	0 to 26.6 K
Mar 18 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President & COO	Option Exercise	M	0.95	24,058	22,855	0
Mar 18 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President & COO	Sell	S	25.00	24,058	601,450	4,572	28.6 K to 4.6 K (-84.03 %)
Mar 18 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President & COO	Buy	M	0.95	24,058	22,855	28,630	4.6 K to 28.6 K (+526.20 %)
Mar 11 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	9.30	6,250	58,125	56,250
Mar 11 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	24.55	6,250	153,415	12,588	18.8 K to 12.6 K (-33.18 %)
Mar 11 2013	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	9.30	6,250	58,125	18,838	12.6 K to 18.8 K (+49.65 %)
Mar 11 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	M	0.95	24,000	22,800	24,058
Mar 11 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Sell	S	24.43	24,000	586,270	4,572	28.6 K to 4.6 K (-84.00 %)
Mar 11 2013	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	M	0.95	24,000	22,800	28,572	4.6 K to 28.6 K (+524.93 %)
Feb 28 2013	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	23.50	28,503	669,900	18,617	47.1 K to 18.6 K (-60.49 %)
Feb 28 2013	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	Chief Executive Off ...	Sell	S	23.47	30,000	704,019	47,120	77.1 K to 47.1 K (-38.90 %)
Feb 12 2013	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP, Chief Business ...	Option Exercise	M	7.10	5,000	35,500	35,000
Feb 12 2013	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP, Chief Business ...	Sell	S	25.00	5,000	125,000	11,681	16.7 K to 11.7 K (-29.97 %)
Feb 12 2013	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP, Chief Business ...	Buy	M	7.10	5,000	35,500	16,681	11.7 K to 16.7 K (+42.80 %)
Jan 24 2013	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	P	20.13	4,967	99,986	14,269	9.3 K to 14.3 K (+53.40 %)
Dec 21 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	A	18.66	10,000	186,600	10,000
Dec 21 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	A	18.66	50,000	933,000	50,000
Dec 21 2012	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP, Chief Business ...	Option Exercise	A	18.66	40,000	746,400	40,000
Dec 21 2012	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Option Exercise	A	18.66	100,000	1,866,000	100,000
Dec 21 2012	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	A	18.66	150,000	2,799,000	150,000
Dec 21 2012	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	4,515	2,145	0
Dec 21 2012	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Option Exercise	M	0.48	14,102	6,698	0
Dec 21 2012	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	14,102	6,698	77,120	63 K to 77.1 K (+22.38 %)
Dec 21 2012	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	M	0.48	4,515	2,145	63,018	58.5 K to 63 K (+7.72 %)
Dec 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	9.14	3,750	34,275	15,000
Dec 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	9.30	6,250	58,125	62,500
Dec 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	7.10	4,777	33,917	30,000
Dec 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	19.00	10,000	190,000	12,588	22.6 K to 12.6 K (-44.27 %)
Dec 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	9.14	3,750	34,275	22,588	18.8 K to 22.6 K (+19.91 %)
Dec 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	9.30	6,250	58,125	18,838	12.6 K to 18.8 K (+49.65 %)
Dec 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	17.00	4,777	81,209	12,588	17.4 K to 12.6 K (-27.51 %)
Dec 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	7.10	4,777	33,917	17,365	12.6 K to 17.4 K (+37.95 %)
Dec 06 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	7.10	2,400	17,040	34,777
Dec 06 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	17.04	2,400	40,896	12,588	15 K to 12.6 K (-16.01 %)
Dec 06 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	7.10	2,400	17,040	14,988	12.6 K to 15 K (+19.07 %)
Dec 04 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	7.10	2,823	20,043	37,177
Dec 04 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	17.03	2,823	48,072	12,588	15.4 K to 12.6 K (-18.32 %)
Dec 04 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	7.10	2,823	20,043	15,411	12.6 K to 15.4 K (+22.43 %)
Dec 04 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	M	7.10	3,750	26,625	11,250
Dec 04 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Sell	S	16.93	3,750	63,472	7,847	11.6 K to 7.8 K (-32.34 %)
Dec 04 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Buy	M	7.10	3,750	26,625	11,597	7.8 K to 11.6 K (+47.79 %)
Oct 11 2012	ALNY	ALNYLAM PHARMACEUT ...	ALNYLAM PHARMACEUTICALS, INC.	10% Owner	Option Exercise	C	0.00	6,150,500	0	0
Oct 11 2012	ALNY	ALNYLAM PHARMACEUT ...	ALNYLAM PHARMACEUTICALS, INC.	10% Owner	Buy	C	0.00	6,150,500	0	6,150,500	0 to 6.2 M
Sep 24 2012	ALNY	ALNYLAM PHARMACEUT ...	NOVARTIS AG	10% Owner	Sell	S	19.42	1,551,896	30,137,820	4,051,002	5.6 M to 4.1 M (-27.70 %)
Jul 31 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	M	10.98	6,250	68,625	18,750
Jul 31 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Sell	S	20.00	6,250	125,000	7,847	14.1 K to 7.8 K (-44.34 %)
Jul 31 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Buy	M	10.98	6,250	68,625	14,097	7.8 K to 14.1 K (+79.65 %)
Sep 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	9.30	4,916	45,719	68,750
Sep 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Option Exercise	M	9.30	1,334	12,406	73,666
Sep 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	19.00	4,916	93,404	12,588	17.5 K to 12.6 K (-28.09 %)
Sep 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	9.30	4,916	45,719	17,504	12.6 K to 17.5 K (+39.05 %)
Sep 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Sell	S	19.00	1,334	25,346	12,588	13.9 K to 12.6 K (-9.58 %)
Sep 12 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	EVP, Chief Medical ...	Buy	M	9.30	1,334	12,406	13,922	12.6 K to 13.9 K (+10.60 %)
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Chief Medical ...	Option Exercise	M	9.30	25,000	232,500	75,000
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Chief Medical ...	Option Exercise	M	9.14	11,250	102,825	18,750
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Chief Medical ...	Sell	S	19.00	11,250	213,750	12,588	23.8 K to 12.6 K (-47.19 %)
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Chief Medical ...	Buy	M	9.14	11,250	102,825	23,838	12.6 K to 23.8 K (+89.37 %)
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Chief Medical ...	Sell	S	19.00	25,000	475,000	12,588	37.6 K to 12.6 K (-66.51 %)
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Chief Medical ...	Buy	M	9.30	25,000	232,500	37,588	12.6 K to 37.6 K (+198.60 %)
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance & Treas ...	Option Exercise	M	13.12	8,733	114,577	8,767
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance & Treas ...	Option Exercise	M	9.14	6,562	59,977	10,938
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance & Treas ...	Sell	S	18.00	6,562	118,116	7,847	14.4 K to 7.8 K (-45.54 %)
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance & Treas ...	Buy	M	9.14	6,562	59,977	14,409	7.8 K to 14.4 K (+83.62 %)
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance & Treas ...	Sell	S	19.00	8,733	165,927	7,847	16.6 K to 7.8 K (-52.67 %)
Jul 18 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance & Treas ...	Buy	M	13.12	8,733	114,577	16,580	7.8 K to 16.6 K (+111.29 %)
Jun 25 2012	ALNY	ALNYLAM PHARMACEUT ...	STARR KEVIN P	Director	Option Exercise	A	11.33	25,000	283,250	25,000
Jun 25 2012	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Option Exercise	A	11.33	30,000	339,900	30,000
Jun 25 2012	ALNY	ALNYLAM PHARMACEUT ...	Fanucci Marsha	Director	Option Exercise	A	11.33	15,000	169,950	15,000
Jun 25 2012	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Option Exercise	A	11.33	15,000	169,950	15,000
Jun 25 2012	ALNY	ALNYLAM PHARMACEUT ...	DZAU VICTOR J	Director	Option Exercise	A	11.33	15,000	169,950	15,000
Jun 25 2012	ALNY	ALNYLAM PHARMACEUT ...	PAUL STEVEN M	Director	Option Exercise	A	11.33	15,000	169,950	15,000
Jun 25 2012	ALNY	ALNYLAM PHARMACEUT ...	CLARKE JOHN K	Director	Option Exercise	A	11.33	15,000	169,950	15,000
Feb 23 2012	ALNY	ALNYLAM PHARMACEUT ...	SHARP PHILIP A	Director	Buy	P	10.75	9,302	99,997	9,302	0 to 9.3 K
Feb 23 2012	ALNY	ALNYLAM PHARMACEUT ...	SCHIMMEL PAUL	Director	Buy	P	10.75	93,023	999,997	252,111	159.1 K to 252.1 K (+58.47 %)
Feb 23 2012	ALNY	ALNYLAM PHARMACEUT ...	Fanucci Marsha	Director	Buy	P	10.75	10,000	107,500	10,000	0 to 10 K
Feb 23 2012	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP, Chief Business ...	Buy	P	10.75	930	9,998	11,681	10.8 K to 11.7 K (+8.65 %)
Feb 23 2012	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	P	10.75	5,581	59,996	58,503	52.9 K to 58.5 K (+10.55 %)
Feb 23 2012	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	P	10.75	1,860	19,995	4,572	2.7 K to 4.6 K (+68.58 %)
Jan 25 2012	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Chief Medical ...	Grant	A	0.00	12,588	0	12,588	0 to 12.6 K
Jan 25 2012	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP, Chief Business ...	Grant	A	0.00	10,751	0	10,751	0 to 10.8 K
Jan 25 2012	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Grant	A	0.00	7,847	0	7,847	0 to 7.8 K
Jan 11 2012	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	P	8.80	567	4,992	2,712	2.1 K to 2.7 K (+26.43 %)
Jan 11 2012	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	P	8.81	1,134	9,995	52,922	51.8 K to 52.9 K (+2.19 %)
Dec 14 2011	ALNY	ALNYLAM PHARMACEUT ...	Greene Barry E	President and COO	Buy	P	7.15	699	4,995	2,145	1.4 K to 2.1 K (+48.34 %)
Dec 14 2011	ALNY	ALNYLAM PHARMACEUT ...	MARAGANORE JOHN	CEO	Buy	P	7.15	1,397	9,995	51,788	50.4 K to 51.8 K (+2.77 %)
Dec 02 2011	ALNY	ALNYLAM PHARMACEUT ...	Mason Michael	VP, Finance and Tre ...	Option Exercise	A	7.10	15,000	106,500	15,000
Dec 02 2011	ALNY	ALNYLAM PHARMACEUT ...	Reid Laurence	SVP, Chief Business ...	Option Exercise	A	7.10	40,000	284,000	40,000
Dec 02 2011	ALNY	ALNYLAM PHARMACEUT ...	Vaishnaw Akshay	SVP, Chief Medical ...	Option Exercise	A	7.10	40,000	284,000	40,000

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