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General | Insiders | Insider Transactions | Monthly Overview | Weekly Overview

Overview of all insider trading transactions in Sirtris Pharmaceuticals, Inc.. Get notifications about new insider transactions in Sirtris Pharmaceuticals, Inc. for free.

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Date	Ticker	Company	Owner	Relationship	Transaction	Code	Cost ($)	Shares	Transaction Value ($)	Total Shares	% Holdings
May 30 2008	SIRT	Sirtris Pharmaceut ...	Brannelly Paul	VP Finance, Treasur ...	Option Exercise	M	0.42	14,643	6,150	19,643
May 30 2008	SIRT	Sirtris Pharmaceut ...	Brannelly Paul	VP Finance, Treasur ...	Buy	M	0.42	14,643	6,150	31,643	17 K to 31.6 K (+86.14 %)
May 30 2008	SIRT	Sirtris Pharmaceut ...	Elliott Peter	Senior VP, Head of ...	Option Exercise	M	1.10	21,428	23,571	35,715
May 30 2008	SIRT	Sirtris Pharmaceut ...	Elliott Peter	Senior VP, Head of ...	Option Exercise	M	0.42	74,404	31,250	89,286
May 30 2008	SIRT	Sirtris Pharmaceut ...	Elliott Peter	Senior VP, Head of ...	Buy	M	1.10	21,428	23,571	234,618	213.2 K to 234.6 K (+10.05 %)
May 30 2008	SIRT	Sirtris Pharmaceut ...	Elliott Peter	Senior VP, Head of ...	Buy	M	0.42	74,404	31,250	213,190	138.8 K to 213.2 K (+53.61 %)
May 30 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Option Exercise	M	1.10	81,032	89,135	204,717
May 30 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Option Exercise	M	0.42	100,764	42,321	83,972
May 30 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Buy	M	1.10	81,032	89,135	744,053	663 K to 744.1 K (+12.22 %)
May 30 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Buy	M	0.42	100,764	42,321	663,021	562.3 K to 663 K (+17.92 %)
Apr 18 2008	SIRT	Sirtris Pharmaceut ...	FRIEDMAN PAUL A	Director	Option Exercise	A	12.83	22,857	293,255	22,857
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.43	800	10,744	152,834	153.6 K to 152.8 K (-0.52 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.42	700	9,394	153,634	154.3 K to 153.6 K (-0.45 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.41	400	5,364	154,334	154.7 K to 154.3 K (-0.26 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.40	229	3,069	154,734	155 K to 154.7 K (-0.15 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.39	100	1,339	154,963	155.1 K to 155 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.38	100	1,338	155,063	155.2 K to 155.1 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.36	800	10,688	155,163	156 K to 155.2 K (-0.51 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.35	100	1,335	155,963	156.1 K to 156 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.33	100	1,333	156,063	156.2 K to 156.1 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.32	100	1,332	156,163	156.3 K to 156.2 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.30	100	1,330	156,263	156.4 K to 156.3 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.29	114	1,515	156,363	156.5 K to 156.4 K (-0.07 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.29	186	2,472	156,477	156.7 K to 156.5 K (-0.12 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.24	100	1,324	156,663	156.8 K to 156.7 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.23	100	1,323	156,763	156.9 K to 156.8 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.22	100	1,322	156,863	157 K to 156.9 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.18	300	3,954	156,963	157.3 K to 157 K (-0.19 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.17	100	1,317	157,263	157.4 K to 157.3 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.16	400	5,264	157,363	157.8 K to 157.4 K (-0.25 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.13	300	3,939	157,763	158.1 K to 157.8 K (-0.19 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.12	300	3,936	158,063	158.4 K to 158.1 K (-0.19 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.09	171	2,239	158,363	158.5 K to 158.4 K (-0.11 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.09	700	9,163	158,534	159.2 K to 158.5 K (-0.44 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.08	100	1,308	159,234	159.3 K to 159.2 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.05	300	3,915	159,334	159.6 K to 159.3 K (-0.19 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.04	100	1,304	159,634	159.7 K to 159.6 K (-0.06 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.03	200	2,606	159,734	159.9 K to 159.7 K (-0.13 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.01	300	3,903	159,934	160.2 K to 159.9 K (-0.19 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	12.99	300	3,897	160,234	160.5 K to 160.2 K (-0.19 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	12.97	400	5,188	160,534	160.9 K to 160.5 K (-0.25 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	12.94	600	7,764	160,934	161.5 K to 160.9 K (-0.37 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	12.93	400	5,172	161,534	161.9 K to 161.5 K (-0.25 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	12.92	600	7,752	161,934	162.5 K to 161.9 K (-0.37 %)
Apr 15 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	12.91	400	5,164	162,534	162.9 K to 162.5 K (-0.25 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.49	699	9,430	162,934	163.6 K to 162.9 K (-0.43 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.48	100	1,348	163,633	163.7 K to 163.6 K (-0.06 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.47	100	1,347	163,733	163.8 K to 163.7 K (-0.06 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.45	601	8,083	163,833	164.4 K to 163.8 K (-0.37 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.44	300	4,032	164,434	164.7 K to 164.4 K (-0.18 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.43	100	1,343	164,734	164.8 K to 164.7 K (-0.06 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.40	337	4,516	164,834	165.2 K to 164.8 K (-0.20 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.39	595	7,967	165,171	165.8 K to 165.2 K (-0.36 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.38	360	4,817	165,766	166.1 K to 165.8 K (-0.22 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.34	260	3,468	166,126	166.4 K to 166.1 K (-0.16 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.33	342	4,559	166,386	166.7 K to 166.4 K (-0.21 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.30	100	1,330	166,728	166.8 K to 166.7 K (-0.06 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.29	500	6,645	166,828	167.3 K to 166.8 K (-0.30 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.27	100	1,327	167,328	167.4 K to 167.3 K (-0.06 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.24	505	6,686	167,428	167.9 K to 167.4 K (-0.30 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.23	700	9,261	167,933	168.6 K to 167.9 K (-0.42 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.22	300	3,966	168,633	168.9 K to 168.6 K (-0.18 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.20	200	2,640	168,933	169.1 K to 168.9 K (-0.12 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.19	1,000	13,190	169,133	170.1 K to 169.1 K (-0.59 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.18	200	2,636	170,133	170.3 K to 170.1 K (-0.12 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.17	300	3,951	170,333	170.6 K to 170.3 K (-0.18 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.16	700	9,212	170,633	171.3 K to 170.6 K (-0.41 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.14	200	2,628	171,333	171.5 K to 171.3 K (-0.12 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.13	100	1,313	171,533	171.6 K to 171.5 K (-0.06 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.09	200	2,617	171,633	171.8 K to 171.6 K (-0.12 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.08	201	2,629	171,833	172 K to 171.8 K (-0.12 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.07	400	5,228	172,034	172.4 K to 172 K (-0.23 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.04	100	1,304	172,434	172.5 K to 172.4 K (-0.06 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.03	100	1,303	172,534	172.6 K to 172.5 K (-0.06 %)
Apr 14 2008	SIRT	Sirtris Pharmaceut ...	Sinclair David	Director	Sell	S	13.02	200	2,604	172,634	172.8 K to 172.6 K (-0.12 %)
Feb 26 2008	SIRT	Sirtris Pharmaceut ...	Brannelly Paul	VP Finance, Treasur ...	Option Exercise	M	0.42	5,000	2,100	34,286
Feb 26 2008	SIRT	Sirtris Pharmaceut ...	Brannelly Paul	VP Finance, Treasur ...	Grant	A	0.00	5,000	0	17,000	12 K to 17 K (+41.67 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.79	500	5,895	562,257	562.8 K to 562.3 K (-0.09 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.76	100	1,176	562,757	562.9 K to 562.8 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.74	100	1,174	562,857	563 K to 562.9 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.70	100	1,170	562,957	563.1 K to 563 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.66	200	2,332	563,057	563.3 K to 563.1 K (-0.04 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.64	100	1,164	563,257	563.4 K to 563.3 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.63	100	1,163	563,357	563.5 K to 563.4 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.62	300	3,486	563,457	563.8 K to 563.5 K (-0.05 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.60	100	1,160	563,757	563.9 K to 563.8 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.59	100	1,159	563,857	564 K to 563.9 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.58	100	1,158	563,957	564.1 K to 564 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.57	100	1,157	564,057	564.2 K to 564.1 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.55	100	1,155	564,157	564.3 K to 564.2 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.54	12	138	564,257	564.3 K to 564.3 K (0.00 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.52	300	3,456	564,269	564.6 K to 564.3 K (-0.05 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.51	700	8,057	564,569	565.3 K to 564.6 K (-0.12 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.50	988	11,362	565,269	566.3 K to 565.3 K (-0.17 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.50	100	1,150	566,257	566.4 K to 566.3 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.49	600	6,894	566,357	567 K to 566.4 K (-0.11 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.48	700	8,036	566,957	567.7 K to 567 K (-0.12 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.47	300	3,441	567,657	568 K to 567.7 K (-0.05 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.46	200	2,292	567,957	568.2 K to 568 K (-0.04 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.40	100	1,140	568,157	568.3 K to 568.2 K (-0.02 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.38	341	3,881	568,257	568.6 K to 568.3 K (-0.06 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.35	269	3,053	568,598	568.9 K to 568.6 K (-0.05 %)
Mar 07 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.25	200	2,250	568,867	569.1 K to 568.9 K (-0.04 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.80	490	5,782	569,067	569.6 K to 569.1 K (-0.09 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.79	200	2,358	569,557	569.8 K to 569.6 K (-0.04 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.78	200	2,356	569,757	570 K to 569.8 K (-0.04 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.77	100	1,177	569,957	570.1 K to 570 K (-0.02 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.76	200	2,352	570,057	570.3 K to 570.1 K (-0.04 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.74	100	1,174	570,257	570.4 K to 570.3 K (-0.02 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.70	100	1,170	570,357	570.5 K to 570.4 K (-0.02 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.69	100	1,169	570,457	570.6 K to 570.5 K (-0.02 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.68	700	8,176	570,557	571.3 K to 570.6 K (-0.12 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.67	300	3,501	571,257	571.6 K to 571.3 K (-0.05 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.65	200	2,330	571,557	571.8 K to 571.6 K (-0.03 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.64	700	8,148	571,757	572.5 K to 571.8 K (-0.12 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.62	200	2,324	572,457	572.7 K to 572.5 K (-0.03 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.61	600	6,966	572,657	573.3 K to 572.7 K (-0.10 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.60	200	2,320	573,257	573.5 K to 573.3 K (-0.03 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.59	200	2,318	573,457	573.7 K to 573.5 K (-0.03 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.57	600	6,942	573,657	574.3 K to 573.7 K (-0.10 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.56	200	2,312	574,257	574.5 K to 574.3 K (-0.03 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.54	200	2,308	574,457	574.7 K to 574.5 K (-0.03 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.36	100	1,136	574,657	574.8 K to 574.7 K (-0.02 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.34	400	4,536	574,757	575.2 K to 574.8 K (-0.07 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.32	100	1,132	575,157	575.3 K to 575.2 K (-0.02 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.31	100	1,131	575,257	575.4 K to 575.3 K (-0.02 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.30	100	1,130	575,357	575.5 K to 575.4 K (-0.02 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.29	800	9,032	575,457	576.3 K to 575.5 K (-0.14 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.28	200	2,256	576,257	576.5 K to 576.3 K (-0.03 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.27	200	2,254	576,457	576.7 K to 576.5 K (-0.03 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.25	450	5,063	576,657	577.1 K to 576.7 K (-0.08 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.24	200	2,248	577,107	577.3 K to 577.1 K (-0.03 %)
Mar 06 2008	SIRT	Sirtris Pharmaceut ...	Westphal Christoph H	President and CEO	Sell	S	11.23	450	5,054	577,307	577.8 K to 577.3 K (-0.08 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Option Exercise	M	1.10	17,000	18,700	134,429
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.56	100	1,156	36,700	36.8 K to 36.7 K (-0.27 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.55	100	1,155	36,800	36.9 K to 36.8 K (-0.27 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.54	200	2,308	36,900	37.1 K to 36.9 K (-0.54 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.52	407	4,689	37,100	37.5 K to 37.1 K (-1.09 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.51	500	5,755	37,507	38 K to 37.5 K (-1.32 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.51	200	2,301	38,007	38.2 K to 38 K (-0.52 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.50	2,191	25,197	38,207	40.4 K to 38.2 K (-5.42 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.49	935	10,743	40,398	41.3 K to 40.4 K (-2.26 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.48	529	6,073	41,333	41.9 K to 41.3 K (-1.26 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.48	938	10,768	41,862	42.8 K to 41.9 K (-2.19 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.47	100	1,147	42,800	42.9 K to 42.8 K (-0.23 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.46	300	3,438	42,900	43.2 K to 42.9 K (-0.69 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.45	300	3,435	43,200	43.5 K to 43.2 K (-0.69 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.44	400	4,576	43,500	43.9 K to 43.5 K (-0.91 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.43	400	4,572	43,900	44.3 K to 43.9 K (-0.90 %)
Feb 22 2008	SIRT	Sirtris Pharmaceut ...	Jirousek Michael	Senior VP, Research	Sell	S	11.42	300	3,426	44,300	44.6 K to 44.3 K (-0.67 %)

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