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General | Insiders | Insider Transactions | Monthly Overview | Weekly Overview

Overview of all insider trading transactions in INSPIRE PHARMACEUTICALS INC. Get notifications about new insider transactions in INSPIRE PHARMACEUTICALS INC for free.

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Date	Ticker	Company	Owner	Relationship	Transaction	Code	Cost ($)	Shares	Transaction Value ($)	Total Shares	% Holdings
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ADAMS ADRIAN	President and CEO	Option Exercise	D	0.00	95,355	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ADAMS ADRIAN	President and CEO	Option Exercise	D	6.35	350,000	2,222,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ADAMS ADRIAN	President and CEO	Sell	D	5.00	446,875	2,234,375	0	446.9 K to 0 (-100.00 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ADAMS ADRIAN	President and CEO	Sell	U	5.00	203,125	1,015,625	446,875	650 K to 446.9 K (-31.25 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	0.00	2,200	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	0.00	2,200	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	0.00	2,600	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	0.00	2,600	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	0.00	22,610	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	14.73	70,000	1,031,100	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	20.30	17,000	345,100	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	12.80	10,000	128,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	15.65	10,000	156,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	9.42	30,000	282,600	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	5.25	30,000	157,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	5.00	20,500	102,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	6.49	12,500	81,125	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	6.35	12,500	79,375	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	5.81	15,000	87,150	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	6.10	15,000	91,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	3.98	12,000	47,760	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	3.49	14,000	48,860	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	4.44	13,250	58,830	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	3.78	13,250	50,085	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	3.79	10,000	37,900	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	3.84	10,000	38,400	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	4.55	13,250	60,288	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	5.10	13,250	67,575	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	6.08	22,000	133,760	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	6.50	22,000	143,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	4.80	26,000	124,800	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Option Exercise	D	7.07	26,000	183,820	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Sell	D	5.00	20,000	100,000	0	20 K to 0 (-100.00 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	SCHACHLE JOSEPH K	EVP, Pulmonary Busi ...	Sell	U	5.00	150	750	20,000	20.2 K to 20 K (-0.74 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	KOVEN ANDREW I	EVP & Chief Admin & ...	Option Exercise	D	0.00	250,000	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	KOVEN ANDREW I	EVP & Chief Admin & ...	Option Exercise	D	0.00	34,291	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	KOVEN ANDREW I	EVP & Chief Admin & ...	Option Exercise	D	6.22	200,000	1,244,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	KOVEN ANDREW I	EVP & Chief Admin & ...	Sell	U	5.00	142,779	713,895	0	142.8 K to 0 (-100.00 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEFF JONATHAN S	Director	Option Exercise	D	0.00	6,873	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEFF JONATHAN S	Director	Option Exercise	D	5.95	50,000	297,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEFF JONATHAN S	Director	Option Exercise	D	5.00	30,000	150,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEFF JONATHAN S	Director	Option Exercise	D	5.05	30,000	151,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEFF JONATHAN S	Director	Option Exercise	D	5.82	10,164	59,154	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEFF JONATHAN S	Director	Sell	U	5.00	22,907,488	114,537,440	0	22.9 M to 0 (-100.00 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ABERCROMBIE GEORGE B	Director	Option Exercise	D	0.00	12,739	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ABERCROMBIE GEORGE B	Director	Option Exercise	D	0.00	6,873	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ABERCROMBIE GEORGE B	Director	Option Exercise	D	6.28	2,371	14,890	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ABERCROMBIE GEORGE B	Director	Option Exercise	D	6.28	18,970	119,132	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ABERCROMBIE GEORGE B	Director	Option Exercise	D	5.82	10,164	59,154	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	ABERCROMBIE GEORGE B	Director	Sell	U	5.00	1,099	5,495	0	1.1 K to 0 (-100.00 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Johnson Charles A	EVP of R&D & Chief ...	Option Exercise	D	0.00	150,000	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Johnson Charles A	EVP of R&D & Chief ...	Option Exercise	D	0.00	27,524	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Johnson Charles A	EVP of R&D & Chief ...	Option Exercise	D	5.11	250,000	1,277,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	0.00	6,873	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	2.76	32,066	88,502	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	16.76	2,000	33,520	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	16.76	4,000	67,040	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	16.76	10,000	167,600	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	6.92	2,000	13,840	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	6.92	4,000	27,680	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	6.92	20,000	138,400	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	4.39	2,000	8,780	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	4.39	4,000	17,560	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	4.39	10,000	43,900	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	5.46	30,000	163,800	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	5.00	30,000	150,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	5.05	30,000	151,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Option Exercise	D	5.82	10,164	59,154	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	FREY KIP	Director	Sell	U	5.00	2,000	10,000	0	2 K to 0 (-100.00 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Hutson Nancy J	Director	Option Exercise	D	0.00	6,873	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Hutson Nancy J	Director	Option Exercise	D	5.40	1,333	7,198	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Hutson Nancy J	Director	Option Exercise	D	5.40	17,778	96,001	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Hutson Nancy J	Director	Option Exercise	D	5.46	30,000	163,800	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Hutson Nancy J	Director	Option Exercise	D	5.00	30,000	150,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Hutson Nancy J	Director	Option Exercise	D	5.05	30,000	151,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Hutson Nancy J	Director	Option Exercise	D	5.82	10,164	59,154	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Hutson Nancy J	Director	Sell	U	5.00	14,800	74,000	0	14.8 K to 0 (-100.00 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	0.00	10,309	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	15.82	23,333	369,128	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	16.76	1,333	22,341	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	16.76	2,000	33,520	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	16.76	4,000	67,040	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	16.76	10,000	167,600	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	8.43	667	5,623	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	8.43	1,334	11,246	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	6.92	4,000	27,680	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	6.92	2,000	13,840	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	6.92	4,000	27,680	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	6.92	20,000	138,400	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	4.39	4,000	17,560	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	4.39	2,000	8,780	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	4.39	4,000	17,560	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	4.39	10,000	43,900	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	5.46	10,000	54,600	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	5.46	30,000	163,800	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	5.00	10,000	50,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	5.00	30,000	150,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	5.05	10,000	50,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	5.05	30,000	151,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Option Exercise	D	5.82	15,246	88,732	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	LEE KENNETH B JR	Director	Sell	U	5.00	2,400	12,000	0	2.4 K to 0 (-100.00 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	0.00	6,873	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	16.76	2,000	33,520	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	16.76	20,000	335,200	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	15.83	1,500	23,745	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	6.92	2,000	13,840	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	6.92	2,000	13,840	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	6.92	10,000	69,200	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	4.39	2,000	8,780	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	4.39	2,000	8,780	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	4.39	10,000	43,900	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	5.46	30,000	163,800	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	5.00	30,000	150,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	5.05	30,000	151,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Kent Richard S	Director	Option Exercise	D	5.82	10,164	59,154	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	0.00	2,200	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	0.00	2,200	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	0.00	2,600	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	0.00	2,600	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	0.00	23,045	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	12.91	40,000	516,400	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	9.42	40,000	376,800	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	5.25	25,000	131,250	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	5.00	20,500	102,500	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	6.49	11,250	73,013	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	6.35	11,250	71,438	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	5.81	10,250	59,553	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	6.10	10,250	62,525	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	3.98	10,250	40,795	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	3.49	10,250	35,773	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	4.44	10,250	45,510	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	3.78	10,250	38,745	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	3.79	13,250	50,218	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	3.84	13,250	50,880	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	4.55	13,250	60,288	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	5.10	13,250	67,575	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	6.08	22,000	133,760	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	6.50	22,000	143,000	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	4.80	26,000	124,800	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Option Exercise	D	7.07	26,000	183,820	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	Brazzell Romulus K	EVP, Medical & Scie ...	Sell	D	5.00	20,000	100,000	0	20 K to 0 (-100.00 %)
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	HOLMER ALAN F	Director	Option Exercise	D	0.00	6,873	0	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	HOLMER ALAN F	Director	Option Exercise	D	6.92	2,000	13,840	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	HOLMER ALAN F	Director	Option Exercise	D	6.92	10,000	69,200	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	HOLMER ALAN F	Director	Option Exercise	D	6.92	2,000	13,840	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	HOLMER ALAN F	Director	Option Exercise	D	4.39	1,333	5,852	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	HOLMER ALAN F	Director	Option Exercise	D	4.39	1,333	5,852	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	HOLMER ALAN F	Director	Option Exercise	D	4.39	6,666	29,264	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	HOLMER ALAN F	Director	Option Exercise	D	3.85	7,500	28,875	0
May 16 2011	ISPH	INSPIRE PHARMACEUT ...	HOLMER ALAN F	Director	Option Exercise	D	5.05	30,000	151,500	0

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